WGO Graded Evidence: Acute Diarrhea in Adults

Level: Meta-analyses, Systematic reviews, Practice guidelines: 22 Abstracts

Legend: : Key Development,  : Very Important,  : Important, [no star]: Special Mention
	Reduced osmolarity oral rehydration solution for treating cholera. Murphy C, Hahn S, Volmink J, Cochrane Database Syst Rev. 2004 Oct 18;(4):CD003754
	Guideline for the management of acute diarrhea in adults. Manatsathit S, Dupont HL, Farthing M, Kositchaiwat C, Leelakusolvong S, Ramakrishna BS, Sabra A, Speelman P, Surangsrirat S, Working Party of the Program Committ of the Bangkok World Congress of Gastroenterology 2002, J Gastroenterol Hepatol. 2002 Feb;17 Suppl:S54-71
	Zinc in the treatment of acute diarrhea: current status and assessment. Hoque KM, Binder HJ, Gastroenterology. 2006 Jun;130(7):2201-5
	Is Lactobacillus rhamnosus GG effective in preventing the onset of antibiotic-associated diarrhoea: a systematic review. Hawrelak JA, Whitten DL, Myers SP, Digestion. 2005;72(1):51-6
	[Improvement in the management of acute diarrhoea in France?] Martinot A, Pruvost I, Aurel M, Hue V, Dubos F, Arch Pediatr. 2007 Oct;14 Suppl 3:S181-5
	[Medication in infectious acute diarrhea in children] Cézard JP, Bellaiche M, Viala J, Hugot JP, Arch Pediatr. 2007 Oct;14 Suppl 3:S169-75
	[Oral rehydration solutions and acute diarrhoea: an update] Mouterde O, Arch Pediatr. 2007 Oct;14 Suppl 3:S165-8
	[Viral acute diarrhea: clinical and evolutive aspects] Olives JP, Mas E, Arch Pediatr. 2007 Oct;14 Suppl 3:S152-5
	[Prevention and treatment of acute diarrhea in infants] Turck D, Arch Pediatr. 2007 Nov;14(11):1375-8
	Meta-analysis: Lactobacillus GG for treating acute diarrhoea in children. Szajewska H, Skórka A, Ruszczyński M, Gieruszczak-Białek D, Aliment Pharmacol Ther. 2007 Apr 15;25(8):871-81
	Loperamide therapy for acute diarrhea in children: systematic review and meta-analysis. Li ST, Grossman DC, Cummings P, PLoS Med. 2007 Mar 27;4(3):e98
	Diarrhoea as a presentation of bird flu infection: a summary on its correlation to outcome in Thai cases. Wiwanitkit V, Gut. 2005 Oct;54(10):1506
	Rotavirus vaccines: an update. Dennehy PH, Curr Opin Pediatr. 2005 Feb;17(1):88-92
	Oral rehydration versus intravenous therapy for treating dehydration due to gastroenteritis in children: a meta-analysis of randomised controlled trials. Bellemare S, Hartling L, Wiebe N, Russell K, Craig WR, McConnell D, Klassen TP, BMC Med. 2004 Apr 15;2:11
	Clinical practice. Acute infectious diarrhea. Thielman NM, Guerrant RL, N Engl J Med. 2004 Jan 1;350(1):38-47
Supplementary evidence:
	Systematic review: racecadotril in the treatment of acute diarrhoea in children. Szajewska H, Ruszczyński M, Chmielewska A, Wieczorek J, Aliment Pharmacol Ther. 2007 Sep 15;26(6):807-13
	IAP Guidelines 2006 on management of acute diarrhea. Bhatnagar S, Lodha R, Choudhury P, Sachdev HP, Shah N, Narayan S, Wadhwa N, Makhija P, Kunnekel K, Ugra D, Indian Academy of Pediatrics, Indian Pediatr. 2007 May;44(5):380-9
	Recombinant human lactoferrin treatment for global health issues: iron deficiency and acute diarrhea. Bethell DR, Huang J, Biometals. 2004 Jun;17(3):337-42
	Treatment of acute diarrhoea: update of guidelines based on a critical interuniversity assessment of medications and current practices. Urbain D, Belaiche J, De Vos M, Fiasse R, Hiele M, Huijghebaert S, Jacobs F, Malonne H, Speelman P, Van Gompel A, Van Gossum A, Van Wijngaerden E, Acta Gastroenterol Belg. 2003 Jul-Sep;66(3):218-26
	Efficacy of probiotic use in acute diarrhea in children: a meta-analysis. Huang JS, Bousvaros A, Lee JW, Diaz A, Davidson EJ, Dig Dis Sci. 2002 Nov;47(11):2625-34
	Meta-analysis: the effect of probiotic administration on antibiotic-associated diarrhoea. Cremonini F, Di Caro S, Nista EC, Bartolozzi F, Capelli G, Gasbarrini G, Gasbarrini A, Aliment Pharmacol Ther. 2002 Aug;16(8):1461-7
	Probiotics in the treatment and prevention of acute infectious diarrhea in infants and children: a systematic review of published randomized, double-blind, placebo-controlled trials. Szajewska H, Mrukowicz JZ, J Pediatr Gastroenterol Nutr. 2001 Oct;33 Suppl 2:S17-25