WGO Graded Evidence: Asymptomatic Gallstone Disease

Level: Clinical Trials: 6 Abstracts

Legend:   : Special Mention  : Important  : Very Important  : Key Development
 
  Early ductal decompression versus conservative management for gallstone pancreatitis with ampullary obstruction: a prospective randomized clinical trial.
JM Acosta, N Katkhouda, KA Debian, SG Groshen, DD Tsao-Wei, TV Berne, Ann Surg. 2006 Jan:33-40
  Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in humans.
HU Marschall, M Wagner, G Zollner, P Fickert, U Diczfalusy, J Gumhold, D Silbert, A Fuchsbichler, L Benthin, R Grundstr&oeig;m, U Gustafsson, S Sahlin, C Einarsson, M Trauner, Gastroenterology. 2005 Aug:476-85
  Ursodeoxycholic acid exerts no beneficial effect in patients with symptomatic gallstones awaiting cholecystectomy.
NG Venneman, MG Besselink, YC Keulemans, GP Vanberge-Henegouwen, MA Boermeester, IA Broeders, PM Go, KJ van Erpecum, Hepatology. 2006 Jun:1276-83
  Ursodeoxycholic acid improves muscle contractility and inflammation in symptomatic gallbladders with cholesterol gallstones.
MP Guarino, P Cong, M Cicala, R Alloni, S Carotti, J Behar, Gut. 2007 Jun:815-20
  Pain persists in many patients five years after removal of the gallbladder: observations from two randomized controlled trials of symptomatic, noncomplicated gallstone disease and acute cholecystitis.
M Vetrhus, T Berhane, O Søreide, K Søndenaa, J Gastrointest Surg. 2005 Jul-Aug:826-31
  Somatosensory changes in the referred pain area before and after cholecystectomy in patients with uncomplicated gallstone disease.
M Stawowy, AM Drewes, L Arendt-Nielsen, P Funch-Jensen, Scand J Gastroenterol. 2006 Jul:833-7