WGO Graded Evidence: Celiac Disease

Level: Clinical Trials: 30 Abstracts

Legend: : Key Development,  : Very Important,  : Important, [no star]: Special Mention
	Ursodeoxycholic acid treatment for patients with postcholecystectomy pain and bile microlithiasis. Okoro N, Patel A, Goldstein M, Narahari N, Cai Q, Gastrointest Endosc. 2008 Jul;68(1):69-74 - PubTypeList: Journal Article, Randomized Controlled Trial
	CT enteroclysis features of uncomplicated celiac disease: retrospective analysis of 44 patients. Soyer P, Boudiaf M, Dray X, Fargeaudou Y, Vahedi K, Aout M, Vicaut E, Hamzi L, Rymer R, Radiology. 2009 Nov;253(2):416-24
	Small-intestinal histopathology and mortality risk in celiac disease. Ludvigsson JF, Montgomery SM, Ekbom A, Brandt L, Granath F, JAMA. 2009 Sep 16;302(11):1171-8
	Clinical trial: gluten microchallenge with wheat-based starch hydrolysates in coeliac disease patients - a randomized, double-blind, placebo-controlled study to evaluate safety. Kaukinen K, Salmi T, Collin P, Huhtala H, Kärjä-Lahdensuu T, Mäki M, Aliment Pharmacol Ther. 2008 Nov 15;28(10):1240-8 - PubTypeList: Journal Article, Randomized Controlled Trial
	Unkilned and large amounts of oats in the coeliac disease diet: a randomized, controlled study. Kemppainen TA, Heikkinen MT, Ristikankare MK, Kosma VM, Sontag-Strohm TS, Brinck O, Salovaara HO, Julkunen RJ, Scand J Gastroenterol. 2008;43(9):1094-101 - PubTypeList: Journal Article, Randomized Controlled Trial
	Optimal band imaging system: a new tool for enhancing the duodenal villous pattern in celiac disease. Cammarota G, Cesaro P, Cazzato A, Fedeli P, Sparano L, Vecchio FM, Larocca LM, Gasbarrini G, Gastrointest Endosc. 2008 Aug;68(2):352-7 - PubTypeList: Clinical Trial, Journal Article
	Pilot study on the correlation of optical coherence tomography with histology in celiac disease and normal subjects. Masci E, Mangiavillano B, Albarello L, Mariani A, Doglioni C, Testoni PA, J Gastroenterol Hepatol. 2007 Dec;22(12):2256-60 - PubTypeList: Clinical Trial, Journal Article
	Video capsule enteroscopy in the diagnosis of celiac disease: a multicenter study. Rondonotti E, Spada C, Cave D, Pennazio M, Riccioni ME, De Vitis I, Schneider D, Sprujevnik T, Villa F, Langelier J, Arrigoni A, Costamagna G, de Franchis R, Am J Gastroenterol. 2007 Aug;102(8):1624-31 - PubTypeList: Journal Article, Multicenter Study
	Detection of Celiac disease in primary care: a multicenter case-finding study in North America. Catassi C, Kryszak D, Louis-Jacques O, Duerksen DR, Hill I, Crowe SE, Brown AR, Procaccini NJ, Wonderly BA, Hartley P, Moreci J, Bennett N, Horvath K, Burk M, Fasano A, Am J Gastroenterol. 2007 Jul;102(7):1454-60 - PubTypeList: Journal Article, Multicenter Study
	Endoscopic and histological findings in the duodenum of adults with celiac disease before and after changing to a gluten-free diet: a 2-year prospective study. Tursi A, Brandimarte G, Giorgetti GM, Elisei W, Inchingolo CD, Monardo E, Aiello F, Endoscopy. 2006 Jul;38(7):702-7 - PubTypeList: Clinical Trial, Journal Article
	Diagnostic accuracy of coeliac serological tests: a prospective study. Reeves GE, Squance ML, Duggan AE, Murugasu RR, Wilson RJ, Wong RC, Gibson RA, Steele RH, Pollock WK, Eur J Gastroenterol Hepatol. 2006 May;18(5):493-501 - PubTypeList: Evaluation Studies, Journal Article, Multicenter Study
	Coeliac disease case finding and diet monitoring by point-of-care testing. Korponay-Szabó IR, Raivio T, Laurila K, Opre J, Király R, Kovács JB, Kaukinen K, Fésüs L, Mäki M, Aliment Pharmacol Ther. 2005 Oct 15;22(8):729-37 - PubTypeList: Evaluation Studies, Journal Article, Multicenter Study
	Antiendomysial and antihuman recombinant tissue transglutaminase antibodies in the diagnosis of coeliac disease: a biopsy-proven European multicentre study. Collin P, Kaukinen K, Vogelsang H, Korponay-Szabó I, Sommer R, Schreier E, Volta U, Granito A, Veronesi L, Mascart F, Ocmant A, Ivarsson A, Lagerqvist C, Bürgin-Wolff A, Hadziselimovic F, Furlano RI, Sidler MA, Mulder CJ, Goerres MS, Mearin ML, Ninaber MK, Gudmand-Høyer E, Fabiani E, Catassi C, Tidlund H, Alainentalo L, Mäki M, Eur J Gastroenterol Hepatol. 2005 Jan;17(1):85-91 - PubTypeList: Evaluation Studies, Journal Article, Multicenter Study
	Interaction between psychiatric and autoimmune disorders in coeliac disease patients in the Northeastern United States. Garud S, Leffler D, Dennis M, Edwards-George J, Saryan D, Sheth S, Schuppan D, Jamma S, Kelly CP, Aliment Pharmacol Ther. 2009 Apr 15;29(8):898-905 Cat: Journal Article
	Clinical trial: B vitamins improve health in patients with coeliac disease living on a gluten-free diet. Hallert C, Svensson M, Tholstrup J, Hultberg B, Aliment Pharmacol Ther. 2009 Apr 15;29(8):811-6 Cat: Journal Article
	Celiac disease and non-organ-specific autoantibodies in patients with chronic hepatitis C virus infection. Ruggeri C, La Masa AT, Rudi S, Squadrito G, Di Pasquale G, Maimone S, Caccamo G, Pellegrino S, Raimondo G, Magazzù G, Dig Dis Sci. 2008 Aug;53(8):2151-5 - PubTypeList: Journal Article, Multicenter Study
	Brush border enzyme activities in relation to histological lesion in pediatric celiac disease. Prasad KK, Thapa BR, Nain CK, Sharma AK, Singh K, J Gastroenterol Hepatol. 2008 Aug;23(8 Pt 2):e348-52 - PubTypeList: Clinical Trial, Journal Article
	The safety, tolerance, pharmacokinetic and pharmacodynamic effects of single doses of AT-1001 in coeliac disease subjects: a proof of concept study. Paterson BM, Lammers KM, Arrieta MC, Fasano A, Meddings JB, Aliment Pharmacol Ther. 2007 Sep 1;26(5):757-66 - PubTypeList: Journal Article, Randomized Controlled Trial
	Budesonide in the treatment of refractory celiac disease. Brar P, Lee S, Lewis S, Egbuna I, Bhagat G, Green PH, Am J Gastroenterol. 2007 Oct;102(10):2265-9 - PubTypeList: Clinical Trial, Journal Article
	A highly accurate method for monitoring histological recovery in patients with celiac disease on a gluten-free diet using an endoscopic approach that avoids the need for biopsy: a double-center study. Cammarota G, Cuoco L, Cesaro P, Santoro L, Cazzato A, Montalto M, La Mura R, Larocca LM, Vecchio FM, Gasbarrini A, Salvagnini M, Gasbarrini G, Endoscopy. 2007 Jan;39(1):46-51 - PubTypeList: Journal Article, Multicenter Study
	Urinary nitric oxide during one year of gluten-free diet with or without oats in children with coeliac disease. Hollén E, Forslund T, Högberg L, Laurin P, Stenhammar L, Fälth-Magnusson K, Magnusson KE, Sundqvist T, Scand J Gastroenterol. 2006 Nov;41(11):1272-8 - PubTypeList: Journal Article, Multicenter Study, Randomized Controlled Trial
	Oats in the treatment of childhood coeliac disease: a 2-year controlled trial and a long-term clinical follow-up study. Holm K, Mäki M, Vuolteenaho N, Mustalahti K, Ashorn M, Ruuska T, Kaukinen K, Aliment Pharmacol Ther. 2006 May 15;23(10):1463-72 - PubTypeList: Journal Article, Randomized Controlled Trial
	Usefulness of the organ culture system in the in vitro diagnosis of coeliac disease: a multicentre study. Picarelli A, Di Tola M, Sabbatella L, Anania MC, Calabrò A, Renzi D, Bai JC, Sugai E, Carroccio A, Di Prima L, Bardella MT, Barisani D, Ribes-Koninckx C, Aliaga ED, Gasparin M, Bravi E, Multicentre Organ Culture System Study Group, Scand J Gastroenterol. 2006 Feb;41(2):186-90 - PubTypeList: Journal Article, Multicenter Study
	European multi-centre study on coeliac disease and non-Hodgkin lymphoma. Mearin ML, Catassi C, Brousse N, Brand R, Collin P, Fabiani E, Schweizer JJ, Abuzakouk M, Szajewska H, Hallert C, Farré Masip C, Holmes GK, Biomed Study Group on Coeliac Disease and Non-Hodgkin Lymphoma, Eur J Gastroenterol Hepatol. 2006 Feb;18(2):187-94 - PubTypeList: Journal Article, Multicenter Study
	Coeliac children on a gluten-free diet with or without oats display equal anti-avenin antibody titres. Hollén E, Holmgren Peterson K, Sundqvist T, Grodzinsky E, Högberg L, Laurin P, Stenhammar L, Fälth-Magnusson K, Magnusson KE, Scand J Gastroenterol. 2006 Jan;41(1):42-7 - PubTypeList: Journal Article, Randomized Controlled Trial
	Enzyme therapy for management of coeliac disease. Cornell HJ, Macrae FA, Melny J, Pizzey CJ, Cook F, Mason S, Bhathal PS, Stelmasiak T, Scand J Gastroenterol. 2005 Nov;40(11):1304-12 - PubTypeList: Journal Article, Randomized Controlled Trial
	Screening detected celiac disease in children with type 1 diabetes mellitus: effect on the clinical course (a case control study). Rami B, Sumnik Z, Schober E, Waldhör T, Battelino T, Bratanic N, Kürti K, Lebl J, Limbert C, Madacsy L, Odink RJ, Paskova M, Soltesz G, J Pediatr Gastroenterol Nutr. 2005 Sep;41(3):317-21 - PubTypeList: Journal Article, Multicenter Study
Supplementary evidence:
	Complications in celiac disease under gluten-free diet. Tursi A, Elisei W, Giorgetti GM, Brandimarte G, Aiello F, Dig Dis Sci. 2009 Oct;54(10):2175-82
	Antiendomysial antibody detection in biopsy culture allows avoidance of gluten challenge in celiac children. Bonamico M, Sabbatella L, Di Tola M, Vetrano S, Ferri M, Nenna R, Mariani P, Picarelli A, J Pediatr Gastroenterol Nutr. 2005 Feb;40(2):165-9; discussion 122-4 - PubTypeList: Clinical Trial, Journal Article, Randomized Controlled Trial
	Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study. Fasano A, Berti I, Gerarduzzi T, Not T, Colletti RB, Drago S, Elitsur Y, Green PH, Guandalini S, Hill ID, Pietzak M, Ventura A, Thorpe M, Kryszak D, Fornaroli F, Wasserman SS, Murray JA, Horvath K, Arch Intern Med. 2003 Feb 10;163(3):286-92 - PubTypeList: Journal Article, Multicenter Study