WGO Graded Evidence: Constipation

Level: Other Reading: 91 Abstracts

Legend:   : Special Mention  : Important  : Very Important  : Key Development
	Chronic constipation in the elderly. Bouras EP, Tangalos EG, Gastroenterol Clin North Am. 2009 Sep;38(3):463-80
	No Role for Increased Rectal Compliance in Pediatric Functional Constipation. Berg MM, Bongers ME, Voskuijl WP, Benninga MA, Gastroenterology. 2009 Aug 21;
	Phenotypic Variation of Colonic Motor Functions in Chronic Constipation. Ravi K, Bharucha AE, Camilleri M, Rhoten D, Bakken T, Zinsmeister AR, Gastroenterology. 2009 Aug 4;
	Childhood functional gastrointestinal disorders: child/adolescent. A Rasquin, C Di Lorenzo, D Forbes, E Guiraldes, JS Hyams, A Staiano, LS Walker, Gastroenterology. 2006 Apr:1527-37
	Experience with type A botulinum toxin for treatment of outlet-type constipation. G Maria, F Cadeddu, F Brandara, G Marniga, G Brisinda, Am J Gastroenterol. 2006 Nov:2570-5
	Functional bowel disorders. GF Longstreth, WG Thompson, WD Chey, LA Houghton, F Mearin, RC Spiller, Gastroenterology. 2006 Apr:1480-91
	Altered bile acid metabolism in patients with constipation-predominant irritable bowel syndrome and functional constipation. Abrahamsson H, Ostlund-Lindqvist AM, Nilsson R, Simrén M, Gillberg PG, Scand J Gastroenterol. 2008;43(12):1483-8 Cat: Journal Article
	Ziziphus jujuba extract for the treatment of chronic idiopathic constipation: a controlled clinical trial. Naftali T, Feingelernt H, Lesin Y, Rauchwarger A, Konikoff FM, Digestion. 2008;78(4):224-8 Cat: Journal Article
	24-Hour colonic manometry in pediatric slow transit constipation shows significant reductions in antegrade propagation. King SK, Catto-Smith AG, Stanton MP, Sutcliffe JR, Simpson D, Cook I, Dinning P, Hutson JM, Southwell BR, Am J Gastroenterol. 2008 Aug;103(8):2083-91
	Incidence of ischemic colitis and serious complications of constipation among patients using alosetron: systematic review of clinical trials and post-marketing surveillance data. L Chang, WD Chey, L Harris, K Olden, C Surawicz, P Schoenfeld, Am J Gastroenterol. 2006 May:1069-79
	Percutaneous endoscopic cecostomy in adults: a case series. CR Lynch, RG Jones, K Hilden, JC Wills, JC Fang, Gastrointest Endosc. 2006 Aug:279-82
	Pilot study of the efficacy of renzapride on gastrointestinal motility and symptoms in patients with constipation-predominant irritable bowel syndrome. J Tack, SJ Middleton, MC Horne, H Piessevaux, JS Bloor, NL Meyers, RM Palmer, Aliment Pharmacol Ther. 2006 Jun 1:1655-65
	Familial Clustering of Habitual Constipation: A Prospective Study in Children From West Virginia. Ostwani W, Dolan J, Elitsur Y, J Pediatr Gastroenterol Nutr. 2009 Aug 4;
	Ambulatory care for constipation in the United States, 1993-2004. Shah ND, Chitkara DK, Locke GR, Meek PD, Talley NJ, Am J Gastroenterol. 2008 Jul;103(7):1746-53
	ASGE guideline: guideline on the use of endoscopy in the management of constipation. W Qureshi, DG Adler, RE Davila, J Egan, WK Hirota, BC Jacobson, JA Leighton, E Rajan, MJ Zuckerman, R Fanelli, J Wheeler-Harbaugh, TH Baron, DO Faigel, Gastrointest Endosc. 2005 Aug:199-201
	Bowel habit subtypes and temporal patterns in irritable bowel syndrome: systematic review. M Guilera, A Balboa, F Mearin, Am J Gastroenterol. 2005 May:1174-84
	Childhood functional gastrointestinal disorders: neonate/toddler. PE Hyman, PJ Milla, MA Benninga, GP Davidson, DF Fleisher, J Taminiau, Gastroenterology. 2006 Apr:1519-26
	Clinical presentation and patterns of slow transit constipation do not predict coexistent upper gut dysmotility. Zarate N, Knowles CH, Yazaki E, Lunnis PJ, Scott SM, Dig Dis Sci. 2009 Jan;54(1):122-31
	Colorectal motor and sensitivity features in patients affected by ulcerative proctitis with constipation: a radiological and manometric controlled study. P Crispino, FI Habib, D Badiali, R Pica, F Iacopini, A Bella, C Cassieri, F Anzini, P Paoluzi, Inflamm Bowel Dis. 2006 Aug:712-8
	Epidemiology of childhood constipation: a systematic review. MM van den Berg, MA Benninga, C Di Lorenzo, Am J Gastroenterol. 2006 Oct:2401-9
	Fiber for the treatment of hemorrhoids complications: a systematic review and meta-analysis. P Alonso-Coello, E Mills, D Heels-Ansdell, M López-Yarto, Q Zhou, JF Johanson, G Guyatt, Am J Gastroenterol. 2006 Jan:181-8
	Food intolerance and chronic constipation: manometry and histology study. G Iacono, S Bonventre, C Scalici, E Maresi, L Di Prima, M Soresi, G Di Gesù, D Noto, A Carroccio, Eur J Gastroenterol Hepatol. 2006 Feb:143-50
	Gallbladder motility in children with chronic constipation. Veras Neto MC, Yamada RM, da Costa Pinto EA, J Pediatr Gastroenterol Nutr 2008 Apr;46(4):414-8
	Review article: Chronic constipation and food hypersensitivity--an intriguing relationship. A Carroccio, G Iacono, Aliment Pharmacol Ther. 2006 Nov 1:1295-304
	Systematic review: the adverse effects of sodium phosphate enema. J Mendoza, J Legido, S Rubio, JP Gisbert, Aliment Pharmacol Ther. 2007 Jul 1:9-20
Supplementary evidence:
	Methanogenic Flora Is Associated With Altered Colonic Transit but Not Stool Characteristics in Constipation Without IBS. Attaluri A, Jackson M, Valestin J, Rao SS, Am J Gastroenterol. 2009 Dec 1;
	Wireless capsule motility: comparison of the SmartPill GI monitoring system with scintigraphy for measuring whole gut transit. Maqbool S, Parkman HP, Friedenberg FK, Dig Dis Sci. 2009 Oct;54(10):2167-74
	A new questionnaire for constipation and faecal incontinence. AE Bharucha, GR Locke 3rd, BM Seide, AR Zinsmeister, Aliment Pharmacol Ther. 2004 Aug 1:355-64
	A population-based study on defecatory conditions in Japanese subjects: methods for self-evaluation. S Nakaji, M Matsuzaka, T Umeda, T Shimoyama, K Sugawara, J Sakamoto, S Wada, S Tokunaga, Tohoku J Exp Med. 2004 Jun:97-104
	Abnormal predefecatory colonic motor patterns define constipation in obstructed defecation. PG Dinning, PA Bampton, J Andre, ML Kennedy, DZ Lubowski, DW King, IJ Cook, Gastroenterology. 2004 Jul:49-56
	Adolescent constipation: evaluation and management. NN Youssef, L Sanders, C Di Lorenzo, Adolesc Med Clin. 2004 Feb:37-52
	Ambulatory 24-hour colonic manometry in slow-transit constipation. SS Rao, P Sadeghi, J Beaty, R Kavlock, Am J Gastroenterol. 2004 Dec:2405-16
	Bowel movement frequency, medical history and the risk of gallbladder cancer death: a cohort study in Japan. K Yagyu, Y Lin, Y Obata, S Kikuchi, T Ishibashi, M Kurosawa, Y Inaba, A Tamakoshi, JACC Study Group, Cancer Sci. 2004 Aug:674-8
	Categorization of dysmotility in patients with chronic constipation and its significance for management. XF Guo, MY Ke, ZF Wang, XC Fang, B Wu, YP Tu, Chin J Dig Dis. 2004:98-102
	Childhood constipation: is there new light in the tunnel? MA Benninga, WP Voskuijl, JA Taminiau, J Pediatr Gastroenterol Nutr. 2004 Nov:448-64
	Chronic constipation F Arguelles Arias, JM Herrerías Gutiérrez, Med Clin (Barc). 2004 Sep 25:389-94
	Chronic constipation and food intolerance: a model of proctitis causing constipation. A Carroccio, C Scalici, E Maresi, L Di Prima, F Cavataio, D Noto, R Porcasi, MR Averna, G Iacono, Scand J Gastroenterol. 2005 Jan:33-42
	Clinical significance of functional constipation categorized by colonic transit time and pelvic floor electromyography. GY Xiong, ZQ Zhao, Chin J Dig Dis. 2004:156-9
	Constipation and intestinal neuronal dysplasia type B: a clinical follow-up study. G Schimpl, E Uray, M Ratschek, ME H&oeig;llwarth, J Pediatr Gastroenterol Nutr. 2004 Mar:308-11
	Constipation, laxative use and risk of colorectal cancer: The Miyagi Cohort Study. T Watanabe, N Nakaya, K Kurashima, S Kuriyama, Y Tsubono, I Tsuji, Eur J Cancer. 2004 Sep:2109-15
	Current treatment options for chronic constipation. JA DiPalma, Rev Gastroenterol Disord. 2004:S34-42
	Definitions, epidemiology, and impact of chronic constipation. NJ Talley, Rev Gastroenterol Disord. 2004:S3-S10
	Diagnosis of constipation in primary and secondary care. A Wald, Rev Gastroenterol Disord. 2004:S28-33
	Dietary fibre: more than a matter of dietetics. II. Preventative and therapeutic uses F Trepel, Wien Klin Wochenschr. 2004 Aug 31:511-22
	Differentiating functional constipation from constipation-predominant irritable bowel syndrome: management implications. NJ Talley, Rev Gastroenterol Disord. 2005 Winter:1-9
	Effects of laxatives: rapid relief or long-term intestinal sluggishness? A Schlegel, Pflege Z. 2004 Jun:382-5
	Health related quality of life in disorders of defecation: the Defecation Disorder List. WP Voskuijl, HJ van der Zaag-Loonen, IJ Ketel, MA Grootenhuis, BH Derkx, MA Benninga, Arch Dis Child. 2004 Dec:1124-7
	Healthcare seeking for constipation: a population-based survey in the Mediterranean area of Spain. C Gálvez, V Garrigues, V Ortiz, M Ponce, P Nos, J Ponce, Aliment Pharmacol Ther. 2006 Jul 15:421-8
	Impact of anal incontinence and chronic constipation on quality of life. H Damon, P Dumas, F Mion, Gastroenterol Clin Biol. 2004 Jan:16-20
	In situ Malone antegrade continence enema in 127 patients: a 6-year experience. CD Herndon, RC Rink, MP Cain, M Lerner, M Kaefer, E Yerkes, AJ Casale, J Urol. 2004 Oct:1689-91
	Increased prevalence of constipation and fecal soiling in a population of obese children. L Fishman, C Lenders, C Fortunato, C Noonan, S Nurko, J Pediatr. 2004 Aug:253-4
	Investigation of the utility of colorectal function tests and Rome II criteria in dyssynergic defecation (Anismus). SS Rao, RS Mudipalli, M Stessman, B Zimmerman, Neurogastroenterol Motil. 2004 Oct:589-96
	Is constipation associated with decreased physical activity in normally active subjects? AK Tuteja, NJ Talley, SK Joos, JV Woehl, DH Hickam, Am J Gastroenterol. 2005 Jan:124-9
	Life style risks of Parkinson's disease: association between decreased water intake and constipation. A Ueki, M Otsuka, J Neurol. 2004 Oct:vII18-23
	Long-term outcome of functional childhood constipation. S Khan, J Campo, JA Bridge, LC Chiappetta, A Wald, C di Lorenzo, Dig Dis Sci. 2007 Jan:64-9
	Long-term results of the antegrade continent enema procedure for constipation in adults. NP Lees, P Hodson, J Hill, RC Pearson, I MacLennan, Colorectal Dis. 2004 Sep:362-8
	MACE or caecostomy button for idiopathic constipation in children: a comparison of complications and outcomes. S Cascio, ME Flett, M De la Hunt, AM Barrett, B Jaffray, Pediatr Surg Int. 2004 Jul:484-7
	Management of chronic constipation. NJ Talley, Rev Gastroenterol Disord. 2004 Winter:18-24
	Measurement of gastrointestinal transit. HC Lin, C Prather, RS Fisher, JH Meyer, RW Summers, M Pimentel, RW McCallum, LM Akkermans, V Loening-Baucke, AMS Task Force Committee on Gastrointestinal Transit, Dig Dis Sci. 2005 Jun:989-1004
	Mucosal neuroendocrine cell abnormalities in patients with chronic constipation. A Kobayashi, H Yokota, H Kobayashi, A Yamataka, T Miyano, Y Hayashida, Asian J Surg. 2004 Jul:197-201
	Myths and misconceptions about chronic constipation. SA Muller-Lissner, MA Kamm, C Scarpignato, A Wald, Am J Gastroenterol. 2005 Jan:232-42
	New and emerging treatment options for chronic constipation. LR Schiller, Rev Gastroenterol Disord. 2004:S43-51
	Obstipation as a paraneoplastic presentation of small cell lung cancer: case report and literature review. S Jun, M Dimyan, KD Jones, U Ladabaum, Neurogastroenterol Motil. 2005 Feb:16-22
	Obstructed defecation HP Bruch, F Fischer, TH Schiedeck, O Schwandner, Chirurg. 2004 Sep:861-70
	Pathogenesis of slow transit and pelvic floor dysfunction: from bench to bedside. MD Crowell, Rev Gastroenterol Disord. 2004:S17-27
	Peptide YY release after colectomy in slow transit constipation. WP Hopman, RM Mollen, JH Kuijpers, JB Jansen, Scand J Gastroenterol. 2004 Aug:727-30
	Percutaneous endoscopic colostomy of the left colon: a new technique for management of intractable constipation in children. DJ Rawat, M Haddad, N Geoghegan, S Clarke, JM Fell, Gastrointest Endosc. 2004 Jul:39-43
	Polyethylene glycol 3350 without electrolytes for the treatment of functional constipation in infants and toddlers. V Loening-Baucke, R Krishna, DS Pashankar, J Pediatr Gastroenterol Nutr. 2004 Nov:536-9
	Polyethylene glycol for constipation in children younger than eighteen months old. S Michail, E Gendy, D Preud'Homme, A Mezoff, J Pediatr Gastroenterol Nutr. 2004 Aug:197-9
	Pregnancy-related constipation. CM Prather, Curr Gastroenterol Rep. 2004 Oct:402-4
	Prevalence of constipation: agreement among several criteria and evaluation of the diagnostic accuracy of qualifying symptoms and self-reported definition in a population-based survey in Spain. V Garrigues, C Gálvez, V Ortiz, M Ponce, P Nos, J Ponce, Am J Epidemiol. 2004 Mar 1:520-6
	Probiotics and prebiotics in the elderly. JM Hamilton-Miller, Postgrad Med J. 2004 Aug:447-51
	Reasons for creation of permanent ileostomy for the management of idiopathic chronic constipation. AM El-Tawil, J Gastroenterol Hepatol. 2004 Aug:844-6
	Rectal hyposensitivity: a disorder of the rectal wall or the afferent pathway? An assessment using the barostat. MA Gladman, LS Dvorkin, PJ Lunniss, NS Williams, SM Scott, Am J Gastroenterol. 2005 Jan:106-14
	Recurrent vomiting and persistent gastroesophageal reflux caused by unrecognized constipation. SM Borowitz, JL Sutphen, Clin Pediatr (Phila). 2004 Jun:461-6
	Responses of anal constipation to biofeedback treatment. X Fernández-Fraga, F Azpiroz, M Casaus, A Aparici, JR Malagelada, Scand J Gastroenterol. 2005 Jan:20-7
	Results of 24-h manometric recording of colonic motor activity with endoluminal instillation of bisacodyl in patients with severe chronic slow transit constipation. S Hervé, G Savoye, A Behbahani, AM Leroi, P Denis, P Ducrotté, Neurogastroenterol Motil. 2004 Aug:397-402
	Role of progesterone signaling in the regulation of G-protein levels in female chronic constipation. ZL Xiao, V Pricolo, P Biancani, J Behar, Gastroenterology. 2005 Mar:667-75
	Scintigraphic assessment of slow transit constipation with special reference to right- or left-sided colonic delay. E Lundin, U Karlbom, JE Westlin, K Kairemo, B Jung, S Husin, L Pċhlman, W Graf, Colorectal Dis. 2004 Nov:499-505
	Significance of Rome II-defined functional constipation in Taiwan and comparison with constipation-predominant irritable bowel syndrome. CL Lu, FY Chang, CY Chen, JC Luo, SD Lee, Aliment Pharmacol Ther. 2006 Jul 15:429-38
	Subtypes of constipation: sorting out the confusion. CM Prather, Rev Gastroenterol Disord. 2004:S11-6
	Surgical management for slow-transit constipation A Alves, B Coffin, Y Panis, Ann Chir. 2004 Oct:400-4
	Tegaserod is effective in the initial and retreatment of irritable bowel syndrome with constipation. S Muller-Lissner, G Holtmann, P Rueegg, G Weidinger, H L&oeig;ffler, Aliment Pharmacol Ther. 2005 Jan 1:11-20
	The APN's guide to pediatric constipation management. D Mason, N Tobias, M Lutkenhoff, M Stoops, D Ferguson, Nurse Pract. 2004 Jul:13-21; quiz 22-3
	The diameter of the rectum on ultrasonography as a diagnostic tool for constipation in children with dysfunctional voiding. AJ Klijn, M Asselman, MA Vijverberg, P Dik, TP de Jong, J Urol. 2004 Nov:1986-8
	The efficacy and safety of polyethylene glycol 3350 in the treatment of constipation in children. MA Kinservik, MM Friedhoff, Pediatr Nurs. 2004 May-Jun:232-7
	The role of pelvic floor dysfunction and slow colonic transit in adolescents with refractory constipation. DK Chitkara, AJ Bredenoord, F Cremonini, S Delgado-Aros, RL Smoot, M El-Youssef, D Freese, M Camilleri, Am J Gastroenterol. 2004 Aug:1579-84
	The treatment of chronic constipation in elderly people: an update. W Bosshard, R Dreher, JF Schnegg, CJ Bula, Drugs Aging. 2004:911-30
	The use of phosphate enemas in the treatment of constipation. C Davies, Nurs Times. 2004 May 4-10:32-5
	Toward a definition of colonic inertia. G Bassotti, GD Roberto, L Sediari, A Morelli, World J Gastroenterol. 2004 Sep 1:2465-7
	Use of Rome II criteria in childhood defecation disorders: applicability in clinical and research practice. WP Voskuijl, J Heijmans, HS Heijmans, JA Taminiau, MA Benninga, J Pediatr. 2004 Aug:213-7
	Visceral sensitivity and symptoms in patients with constipation- or diarrhea-predominant irritable bowel syndrome (IBS): effect of a low-fat intraduodenal infusion. MP Caldarella, A Milano, F Laterza, F Sacco, C Balatsinou, D Lapenna, SD Pierdomenico, F Cuccurullo, M Neri, Am J Gastroenterol. 2005 Feb:383-9
	What is evidence based in the therapy of pelvic floor insufficiency? HP Bruch, O Schwandner, Chirurg. 2004 Sep:849