Legend: : Special Mention  : Important : Very Important : Key Development |
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Double-blind, placebo-controlled trial with single-dose pantoprazole for laryngopharyngeal reflux.
JM Wo, J Koopman, SP Harrell, K Parker, W Winstead, E Lentsch, Am J Gastroenterol. 2006 Sep:1972-8; quiz 2169 |
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Endoscopic full-thickness plication for the treatment of gastroesophageal reflux disease: A randomized, sham-controlled trial.
R Rothstein, C Filipi, K Caca, R Pruitt, K Mergener, A Torquati, G Haber, Y Chen, K Chang, D Wong, J Deviere, D Pleskow, C Lightdale, A Ades, R Kozarek, W Richards, A Lembo, Gastroenterology. 2006 Sep:704-12 |
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The rise and fall (and rise?) of endoscopic anti-reflux procedures.
NJ Shaheen, Gastroenterology. 2006 Sep:952-4 |
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A prospective, randomized, double-blind, placebo-controlled trial of endoscopic steroid injection therapy for recalcitrant esophageal peptic strictures.
JI Ramage Jr, A Rumalla, TH Baron, NL Pochron, AR Zinsmeister, JA Murray, ID Norton, N Diehl, Y Romero, Am J Gastroenterol. 2005 Nov:2419-25 |
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Differences in ERK activation in squamous mucosa in patients who have gastroesophageal reflux disease with and without Barrett's esophagus.
RF Souza, KL Shewmake, Y Shen, RD Ramirez, JS Bullock, CL Hladik, EL Lee, LS Terada, SJ Spechler, Am J Gastroenterol. 2005 Mar:551-9 |
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Endoscopic gastroplication for the treatment of gastro-oesophageal reflux disease: a randomised, sham-controlled trial.
MP Schwartz, H Wellink, HG Gooszen, JM Conchillo, M Samsom, AJ Smout, Gut. 2007 Jan:20-8 |
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Multicenter, randomized, double-blind study comparing 10, 20 and 40 mg pantoprazole in children (5-11 years) with symptomatic gastroesophageal reflux disease.
V Tolia, PR Bishop, VM Tsou, D Gremse, EF Soffer, GM Comer, Members of the 322 Study Group, J Pediatr Gastroenterol Nutr. 2006 Apr:384-91 |
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New design esophageal stents for the palliation of dysphagia from esophageal or gastric cardia cancer: a randomized trial.
EM Verschuur, A Repici, EJ Kuipers, EW Steyerberg, PD Siersema, Am J Gastroenterol. 2008 Feb:304-12 |
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Nonresorbable copolymer implantation for gastroesophageal reflux disease: a randomized sham-controlled multicenter trial.
J Devière, G Costamagna, H Neuhaus, W Voderholzer, H Louis, A Tringali, M Marchese, T Fiedler, P Darb-Esfahani, B Schumacher, Gastroenterology. 2005 Mar:532-40 |
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Relationship between intragastric acid control and healing status in the treatment of moderate to severe erosive oesophagitis.
PO Katz, GG Ginsberg, PE Hoyle, MB Sostek, JT Monyak, DG Silberg, Aliment Pharmacol Ther. 2007 Mar 1:617-28 |
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Twelve months' follow-up after treatment with the EndoCinch endoscopic technique for gastro-oesophageal reflux disease: a randomized, placebo-controlled study.
M Montgomery, B Håkanson, O Ljungqvist, B Ahlman, A Thorell, Scand J Gastroenterol. 2006 Dec:1382-9 |
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Wireless esophageal pH monitoring is better tolerated than the catheter-based technique: results from a randomized cross-over trial.
J Wenner, F Johnsson, J Johansson, S Oberg, Am J Gastroenterol. 2007 Feb:239-45 |
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A randomized prospective comparison of self-expandable plastic stents and partially covered self-expandable metal stents in the palliation of malignant esophageal dysphagia.
M Conio, A Repici, G Battaglia, G De Pretis, L Ghezzo, M Bittinger, H Messmann, JF Demarquay, S Blanchi, M Togni, R Conigliaro, R Filiberti, Am J Gastroenterol. 2007 Dec:2667-77 |
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Acid challenge to the esophageal mucosa: effects on local nitric oxide formation and its relation to epithelial functions.
M Bove, M Vieth, A Casselbrant, L Ny, L Lundell, M Ruth, Dig Dis Sci. 2005 Apr:640-8 |
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Acid control with esomeprazole and lansoprazole: a comparative dose-response study.
C Wilder-Smith, T Lind, C Lundin, E Nauclér, C Nilsson-Pieschl, K R&oeig;hss, Scand J Gastroenterol. 2007 Feb:157-64 |
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Comparison of gastric pH with omeprazole magnesium 20.6 mg (Prilosec OTC) o.m. famotidine 10 mg (Pepcid AC) b.d. and famotidine 20 mg b.d. over 14 days of treatment.
PB Miner Jr, LD Allgood, JM Grender, Aliment Pharmacol Ther. 2007 Jan 1:103-9 |
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Comparison of the effects of immediate-release omeprazole oral suspension, delayed-release lansoprazole capsules and delayed-release esomeprazole capsules on nocturnal gastric acidity after bedtime do
PO Katz, FK Koch, ED Ballard, RG Bagin, TC Gautille, GC Checani, DL Hogan, VS Pratha, Aliment Pharmacol Ther. 2007 Jan 15:197-205 |
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Comparison of the effects of intravenously and orally administered esomeprazole on acid output in patients with symptoms of gastro-oesophageal reflux disease.
DC Metz, PB Miner, DM Heuman, Y Chen, M Sostek, Aliment Pharmacol Ther. 2005 Nov 1:813-21 |
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Discontinuation of proton pump inhibitors in patients on long-term therapy: a double-blind, placebo-controlled trial.
E Bj&oeig;rnsson, H Abrahamsson, M Simrén, N Mattsson, C Jensen, P Agerforz, A Kilander, Aliment Pharmacol Ther. 2006 Sep 15:945-54 |
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Effect of dietary sodium chloride on gastro-oesophageal reflux: a randomized controlled trial.
MC Aanen, AJ Bredenoord, AJ Smout, Scand J Gastroenterol. 2006 Oct:1141-6 |
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Effect of rabeprazole and omeprazole on the onset of gastro-oesophageal reflux disease symptom relief during the first seven days of treatment.
P Bytzer, A Morocutti, P Kennerly, M Ravic, N Miller, ROSE Trial Investigators, Scand J Gastroenterol. 2006 Oct:1132-40 |
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Efficacy of pantoprazole 20 mg daily compared with esomeprazole 20 mg daily in the maintenance of healed gastroesophageal reflux disease: a randomized, double-blind comparative trial - the EMANCIPATE
KL Goh, R Benamouzig, P Sander, T Schwan, EMANCIPATE, Eur J Gastroenterol Hepatol. 2007 Mar:205-11 |
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Efficacy of rabeprazole in the treatment of symptomatic gastroesophageal reflux disease.
PJ Kahrilas, P Miner, J Johanson, L Mao, L Jokubaitis, S Sloan, Dig Dis Sci. 2005 Nov:2009-18 |
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Efficacy of rabeprazole on heartburn symptom resolution in patients with non-erosive and erosive gastro-oesophageal reflux disease: a multicenter study from Japan.
H Miwa, M Sasaki, T Furuta, T Koike, Y Habu, M Ito, Y Fujiwara, T Wada, A Nagahara, M Hongo, T Chiba, Y Kinoshita, ACID-RELATED SYMPTOM (ARS) RESEARCH GROUP, Aliment Pharmacol Ther. 2007 Jul 1:69-77 |
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Endoscopic holder-assisted percutaneous endoscopic gastrostomy placement: results of a prospective, randomized comparison study.
A Horiuchi, Y Nakayama, H Fujii, M Kajiyama, Gastrointest Endosc. 2006 Oct:627-31 |
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Injection of botulinum toxin before pneumatic dilatation in achalasia treatment: a randomized-controlled trial.
J Mikaeli, F Bishehsari, G Montazeri, M Mahdavinia, M Yaghoobi, S Darvish-Moghadam, F Farrokhi, S Shirani, A Estakhri, R Malekzadeh, Aliment Pharmacol Ther. 2006 Sep 15:983-9 |
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Intravenous pantoprazole as initial treatment in patients with gastroesophageal reflux disease and a history of erosive esophagitis: a randomized clinical trial.
V Pratha, DL Hogan, RB Lynn, B Field, DC Metz, Dig Dis Sci. 2006 Sep:1595-601 |
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Long-term outcome is worse after laparoscopic than after conventional Nissen fundoplication.
T Franzén, B Anderberg, M Wirén, KE Johansson, Scand J Gastroenterol. 2005 Nov:1261-8 |
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Management of symptoms in step-down therapy of gastroesophageal reflux disease.
S Mine, T Iida, T Tabata, H Kishikawa, Y Tanaka, J Gastroenterol Hepatol. 2005 Sep:1365-70 |
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Office-based unsedated small-caliber endoscopy is equivalent to conventional sedated endoscopy in screening and surveillance for Barrett's esophagus: a randomized and blinded comparison.
BA Jobe, JG Hunter, EY Chang, CY Kim, GM Eisen, JD Robinson, BS Diggs, RW O'Rourke, AE Rader, P Schipper, DA Sauer, JH Peters, DA Lieberman, CD Morris, Am J Gastroenterol. 2006 Dec:2693-703 |
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On-demand therapy with pantoprazole 20 mg as effective long-term management of reflux disease in patients with mild GERD: the ORION trial.
T Scholten, CP Dekkers, K Schutze, T K&oeig;rner, M Bohuschke, G Gatz, Digestion. 2005:76-85 |
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Oral pantoprazole in the form of granules or tablets are pharmacodynamically equivalent in suppressing acid output in patients with gastro-oesophageal reflux disease and a history of erosive oesophagi
D Hogan, V Pratha, D Riff, S Ducker, H Schwartz, E Soffer, W Wang, N Rath, GM Comer, Aliment Pharmacol Ther. 2007 Jul 15:249-56 |
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Randomised controlled trial of effects of Helicobacter pylori infection and its eradication on heartburn and gastro-oesophageal reflux: Bristol helicobacter project.
RF Harvey, JA Lane, LJ Murray, IM Harvey, JL Donovan, P Nair, Bristol Helicobacter Project, BMJ. 2004 Jun 12:1417 |
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The safety of proton pump inhibitors in pregnancy: a multicentre prospective controlled study.
O Diav-Citrin, J Arnon, S Shechtman, C Schaefer, MR van Tonningen, M Clementi, M De Santis, E Robert-Gnansia, E Valti, H Malm, A Ornoy, Aliment Pharmacol Ther. 2005 Feb 1:269-75 |
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White wine and beer induce gastro-oesophageal reflux in patients with reflux disease.
C Pehl, B Wendl, A Pfeiffer, Aliment Pharmacol Ther. 2006 Jun 1:1581-6 |
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A clinical trial comparing pantoprazole and esomeprazole to explore the concept of achieving 'complete remission' in gastro-oesophageal reflux disease.
KD Bardhan, A Achim, T Riddermann, B Pfaffenberger, Aliment Pharmacol Ther. 2007 Jun 15:1461-9 |
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A randomised prospective comparison of the Flamingo Wallstent and Ultraflex stent for palliation of dysphagia associated with lower third oesophageal carcinoma.
T Sabharwal, MS Hamady, S Chui, S Atkinson, R Mason, A Adam, Gut. 2003 Jul:922-6 |
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An ongoing randomized clinical trial in dysphagia.
J Robbins, J Hind, J Logemann, J Commun Disord. 2004 Sep-Oct:425-35 |
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Dysphagia in patients with erosive esophagitis: prevalence, severity, and response to proton pump inhibitor treatment.
NB Vakil, B Traxler, D Levine, Clin Gastroenterol Hepatol. 2004 Aug:665-8 |
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Effectiveness of esophageal dilation in relieving nonobstructive esophageal dysphagia and improving quality of life.
K Lavu, TP Mathew, A Minocha, South Med J. 2004 Feb:137-40 |
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Empiric Dilation in Non-obstructive Dysphagia.
JS Olson, DA Lieberman, A Sonnenberg, Dig Dis Sci. 2008 May:1192-7 |
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Influence of cytochrome P450 2C19 genetic polymorphism and dosage of rabeprazole on accuracy of proton-pump inhibitor testing in Chinese patients with gastroesophageal reflux disease.
YC Lee, JT Lin, HP Wang, HM Chiu, MS Wu, J Gastroenterol Hepatol. 2007 Aug:1286-92 |
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Prospective, randomized outcome study of endoscopy versus modified barium swallow in patients with dysphagia.
Y Finkelstein, Laryngoscope. 2002 Feb:409-12 |
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Rehabilitation of swallowing by exercise in tube-fed patients with pharyngeal dysphagia secondary to abnormal UES opening.
R Shaker, C Easterling, M Kern, T Nitschke, B Massey, S Daniels, B Grande, M Kazandjian, K Dikeman, Gastroenterology. 2002 May:1314-21 |
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Single-dose brachytherapy versus metal stent placement for the palliation of dysphagia from oesophageal cancer: multicentre randomised trial.
MY Homs, EW Steyerberg, WM Eijkenboom, HW Tilanus, LJ Stalpers, JF Bartelsman, JJ van Lanschot, HK Wijrdeman, CJ Mulder, JG Reinders, H Boot, BM Aleman, EJ Kuipers, PD Siersema, Lancet. 2004 Oct 23-29:1497-504 |
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The value of scintigraphy in the evaluation of oropharyngeal dysphagia.
M Argon, Y Secil, U Duygun, I Aydogdu, K Kocacelebi, H Ozkilic, C Ertekin, Eur J Nucl Med Mol Imaging. 2004 Jan:94-8 |
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Theophylline-improved swallowing reflex in elderly nursing home patients.
T Ebihara, S Ebihara, T Okazaki, H Takahashi, A Wantando, H Yasuda, H Sasaki, J Am Geriatr Soc. 2004 Oct:1787-8 |
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Value of radiotherapy and chemotherapy after SEMS implantation operation in patients with malignant esophageal stricture
YT Han, L Peng, Q Fang, Q Li, Ai Zheng. 2004 Jun:682-4 |