WGO Graded Evidence: Malabsorption

Level: Meta-analyses, Systematic reviews, Practice guidelines: 78 Abstracts

Legend:   : Special Mention  : Important  : Very Important  : Key Development
	National Institutes of Health Consensus Development Conference: lactoseintolerance and health. Suchy FJ, Brannon PM, Carpenter TO, Fernandez JR, Gilsanz V, Gould JB, Hall K,Hui SL, Lupton J, Mennella J, Miller NJ, Osganian SK, Sellmeyer DE, Wolf MA., Ann Intern Med. 2010 Jun 15;152(12):792-6. Epub 2010 Apr 19.
	Causes and management of intestinal failure in children. O Goulet, F Ruemmele, Gastroenterology. 2006 Feb:S16-28
	Natural variation in toxicity of wheat: potential for selection of nontoxic varieties for celiac disease patients. L Spaenij-Dekking, Y Kooy-Winkelaar, P van Veelen, JW Drijfhout, H Jonker, L van Soest, MJ Smulders, D Bosch, LJ Gilissen, F Koning, Gastroenterology. 2005 Sep:797-806
	Systematic review: effective management strategies for lactose intolerance. Shaukat A, Levitt MD, Taylor BC, MacDonald R, Shamliyan TA, Kane RL, Wilt TJ., Ann Intern Med. 2010 Jun 15;152(12):797-803. Epub 2010 Apr 19.
	Meta-analysis: deamidated gliadin peptide antibody and tissue transglutaminaseantibody compared as screening tests for coeliac disease. Lewis NR, Scott BB., Aliment Pharmacol Ther. 2010 Jan;31(1):73-81.
	A genetic test which can be used to diagnose adult-type hypolactasia in children. H Rasinperæ, E Savilahti, NS Enattah, M Kuokkanen, N T&oeig;tterman, H Lindahl, I Jærvelæ, KL Kolho, Gut. 2004 Nov:1571-6
	Antagonists and non-toxic variants of the dominant wheat gliadin T cell epitope in coeliac disease. RP Anderson, DA van Heel, JA Tye-Din, DP Jewell, AV Hill, Gut. 2006 Apr:485-91
	Celiac disease with mild to moderate histologic changes is a common cause of chronic diarrhea in Indian children. S Bhatnagar, SD Gupta, M Mathur, AD Phillips, R Kumar, S Knutton, DJ Unsworth, J Unsworth, RJ Lock, B Lock, UC Natchu, S Mukhopadhyaya, S Saini, MK Bhan, J Pediatr Gastroenterol Nutr. 2005 Aug:204-9
	Coeliac disease and the risk of fractures - a general population-based cohort study. JF Ludvigsson, K Michaelsson, A Ekbom, SM Montgomery, Aliment Pharmacol Ther. 2007 Feb 1:273-85
	Concordance, disease progression, and heritability of coeliac disease in Italian twins. L Nisticò, C Fagnani, I Coto, S Percopo, R Cotichini, MG Limongelli, F Paparo, S D'Alfonso, M Giordano, C Sferlazzas, G Magazzù, P Momigliano-Richiardi, L Greco, MA Stazi, Gut. 2006 Jun:803-8
	Detection of Celiac disease in primary care: a multicenter case-finding study in North America. C Catassi, D Kryszak, O Louis-Jacques, DR Duerksen, I Hill, SE Crowe, AR Brown, NJ Procaccini, BA Wonderly, P Hartley, J Moreci, N Bennett, K Horvath, M Burk, A Fasano, Am J Gastroenterol. 2007 Jul:1454-60
	Determinants of endomysial antibody status in untreated coeliac disease. CP Boger, PW Thomas, DS Nicholas, SL Surgenor, JA Snook, Eur J Gastroenterol Hepatol. 2007 Oct:890-5
	Etiology and initial management of short bowel syndrome. AL Buchman, Gastroenterology. 2006 Feb:S5-S15
	Guidelines for management of patients with a short bowel. J Nightingale, JM Woodward, Small Bowel and Nutrition Committee of the British Society of Gastroenterology, Gut. 2006 Aug:iv1-12
	Gut adaptation and the glucagon-like peptides. DJ Drucker, Gut. 2002 Mar:428-35
	High prevalence of celiac disease in patients with lactose intolerance. V Ojetti, G Nucera, A Migneco, M Gabrielli, C Lauritano, S Danese, MA Zocco, EC Nista, G Cammarota, A De Lorenzo, G Gasbarrini, A Gasbarrini, Digestion. 2005:106-10
	Home parenteral nutrition: survival, cost, and quality of life. L Howard, Gastroenterology. 2006 Feb:S52-9
	Intestinal T cell responses to cereal proteins in celiac disease. C Kilmartin, H Wieser, M Abuzakouk, J Kelly, J Jackson, C Feighery, Dig Dis Sci. 2006 Jan:202-9
	Is exocrine pancreatic insufficiency in adult coeliac disease a cause of persisting symptoms? JS Leeds, AD Hopper, DP Hurlstone, SJ Edwards, ME McAlindon, AJ Lobo, MT Donnelly, S Morley, DS Sanders, Aliment Pharmacol Ther. 2007 Feb 1:265-71
	Long-term mortality in people with celiac disease diagnosed in childhood compared with adulthood: a population-based cohort study. M Solaymani-Dodaran, J West, RF Logan, Am J Gastroenterol. 2007 Apr:864-70
	Screening detected celiac disease in children with type 1 diabetes mellitus: effect on the clinical course (a case control study). B Rami, Z Sumnik, E Schober, T Waldh&oeig;r, T Battelino, N Bratanic, K Kurti, J Lebl, C Limbert, L Madacsy, RJ Odink, M Paskova, G Soltesz, J Pediatr Gastroenterol Nutr. 2005 Sep:317-21
	Screening for celiac disease in family members: is follow-up testing necessary? D Goldberg, D Kryszak, A Fasano, PH Green, Dig Dis Sci. 2007 Apr:1082-6
	Short bowel syndrome: parenteral nutrition versus intestinal transplantation. Where are we today? M DeLegge, MM Alsolaiman, E Barbour, S Bassas, MF Siddiqi, NM Moore, Dig Dis Sci. 2007 Apr:876-92
	Small intestinal bacterial overgrowth: roles of antibiotics, prebiotics, and probiotics. EM Quigley, R Quera, Gastroenterology. 2006 Feb:S78-90
	Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant glucagon-like peptide 2 analogue, improves intestinal function in short bowel syndrome patients. PB Jeppesen, EL Sanguinetti, A Buchman, L Howard, JS Scolapio, TR Ziegler, J Gregory, KA Tappenden, J Holst, PB Mortensen, Gut. 2005 Sep:1224-31
	Undiagnosed silent coeliac disease: a risk for underachievement? MA Verkasalo, OT Raitakari, J Viikari, J Marniemi, E Savilahti, Scand J Gastroenterol. 2005 Dec:1407-12
	Unexpected role of surface transglutaminase type II in celiac disease. L Maiuri, C Ciacci, I Ricciardelli, L Vacca, V Raia, A Rispo, M Griffin, T Issekutz, S Quaratino, M Londei, Gastroenterology. 2005 Nov:1400-13
	Where are all those patients with Celiac disease? PH Green, Am J Gastroenterol. 2007 Jul:1461-3
	A highly accurate method for monitoring histological recovery in patients with celiac disease on a gluten-free diet using an endoscopic approach that avoids the need for biopsy: a double-center study. G Cammarota, L Cuoco, P Cesaro, L Santoro, A Cazzato, M Montalto, R La Mura, LM Larocca, FM Vecchio, A Gasbarrini, M Salvagnini, G Gasbarrini, Endoscopy. 2007 Jan:46-51
	Anti-tissue transglutaminase antibodies in patients with abnormal liver tests: is it always coeliac disease? O Lo Iacono, S Petta, G Venezia, V Di Marco, G Tarantino, F Barbaria, C Mineo, S De Lisi, PL Almasio, A Craxì, Am J Gastroenterol. 2005 Nov:2472-7
	Applicability of short hydrogen breath test for screening of lactose malabsorption. F Casellas, JR Malagelada, Dig Dis Sci. 2003 Jul:1333-8
	Autoantibodies against soluble and immobilized human recombinant tissue transglutaminase in children with celiac disease. D Agardh, I Dahlbom, T Daniels, E L&oeig;rinc, SA Ivarsson, A Lernmark, T Hansson, J Pediatr Gastroenterol Nutr. 2005 Sep:322-7
	Avenins from different cultivars of oats elicit response by coeliac peripheral lymphocytes. M Silano, R Di Benedetto, F Maialetti, A De Vincenzi, R Calcaterra, HJ Cornell, M De Vincenzi, Scand J Gastroenterol. 2007 Nov:1302-5
	Capsule endoscopy changes patient management in routine clinical practice. R Sidhu, DS Sanders, K Kapur, DP Hurlstone, ME McAlindon, Dig Dis Sci. 2007 May:1382-6
	Coeliac disease case finding and diet monitoring by point-of-care testing. IR Korponay-Szabó, T Raivio, K Laurila, J Opre, R Király, JB Kovács, K Kaukinen, L Fésus, M Mæki, Aliment Pharmacol Ther. 2005 Oct 15:729-37
	Deficient UDP-glucuronosyltransferase detoxification enzyme activity in the small intestinal mucosa of patients with coeliac disease. M Goerres, HM Roelofs, JB Jansen, WH Peters, Aliment Pharmacol Ther. 2006 Jan 15:243-6
	Detection of secretory IgA antibodies against gliadin and human tissue transglutaminase in stool to screen for coeliac disease in children: validation study. M Kappler, S Krauss-Etschmann, V Diehl, H Zeilhofer, S Koletzko, BMJ. 2006 Jan 28:213-4
	Duodenal cytotoxic lymphocytes in cow's milk protein sensitive enteropathy and coeliac disease. MT Augustin, J Kokkonen, TJ Karttunen, Scand J Gastroenterol. 2005 Dec:1398-406
	Effect of nonabsorbed amounts of a fructose-sorbitol mixture on small intestinal transit in healthy volunteers. JL Madsen, J Linnet, JJ Rumessen, Dig Dis Sci. 2006 Jan:147-53
	Gut microflora associated characteristics in children with celiac disease. B Tjellstr&oeig;m, L Stenhammar, L H&oeig;gberg, K Fælth-Magnusson, KE Magnusson, T Midtvedt, T Sundqvist, E Norin, Am J Gastroenterol. 2005 Dec:2784-8
	High prevalence of celiac disease among patients affected by Crohn's disease. A Tursi, GM Giorgetti, G Brandimarte, W Elisei, Inflamm Bowel Dis. 2005 Jul:662-6
	How good is zoom endoscopy for assessment of villous atrophy in coeliac disease? R Badreldin, P Barrett, DA Wooff, J Mansfield, Y Yiannakou, Endoscopy. 2005 Oct:994-8
	In vitro tests indicate that certain varieties of oats may be harmful to patients with coeliac disease. M Silano, M Dessì, M De Vincenzi, H Cornell, J Gastroenterol Hepatol. 2007 Apr:528-31
	Intestinal permeability and antigliadin antibody test for monitoring adult patients with celiac disease. EG Vilela, Mde L de Abreu Ferrari, HO de Gama Torres, FP Martins, EM Goulart, AS Lima, AS da Cunha, Dig Dis Sci. 2007 May:1304-9
	Introducing genetic testing for adult-type hypolactasia. C Buning, J Genschel, J Jurga, T Fiedler, W Voderholzer, EM Fiedler, M Worm, R Weltrich, H Lochs, H Schmidt, J Ockenga, Digestion. 2005:245-50
	Metalloelastase (MMP-12) is upregulated in the gut of pediatric patients with potential celiac disease and in type 1 diabetes. V Bister, KL Kolho, R Karikoski, M Westerholm-Ormio, E Savilahti, U Saarialho-Kere, Scand J Gastroenterol. 2005 Dec:1413-22
	No observed local immunological response at cell level after five years of oats in adult coeliac disease. T Kemppainen, E Janatuinen, K Holm, VM Kosma, M Heikkinen, M Mæki, K Laurila, M Uusitupa, R Julkunen, Scand J Gastroenterol. 2007 Jan:54-9
	Parenteral nutrition: transient or permanent therapy in intestinal failure? TR Ziegler, LM Leader, Gastroenterology. 2006 Feb:S37-42
	Peripheral neurological disturbances, autonomic dysfunction, and antineuronal antibodies in adult celiac disease before and after a gluten-free diet. A Tursi, GM Giorgetti, C Iani, F Arciprete, G Brandimarte, A Capria, L Fontana, Dig Dis Sci. 2006 Oct:1869-74
	Population screening for celiac disease: follow up of patients identified by positive serology. R Shamir, V Yehezkely-Schildkraut, C Hartman, R Eliakim, J Gastroenterol Hepatol. 2007 Apr:532-5
	Predictors of reduced health-related quality of life in adults with coeliac disease. W Hæuser, A Stallmach, WF Caspary, J Stein, Aliment Pharmacol Ther. 2007 Mar 1:569-78
	Reduced chemokine receptor 9 on intraepithelial lymphocytes in celiac disease suggests persistent epithelial activation. RW Olaussen, MR Karlsson, KE Lundin, J Jahnsen, P Brandtzaeg, IN Farstad, Gastroenterology. 2007 Jun:2371-82
	Review article: fructose malabsorption and the bigger picture. PR Gibson, E Newnham, JS Barrett, SJ Shepherd, JG Muir, Aliment Pharmacol Ther. 2007 Feb 15:349-63
	Risk of celiac disease autoimmunity and timing of gluten introduction in the diet of infants at increased risk of disease. S Guandalini, J Pediatr Gastroenterol Nutr. 2005 Sep:366-7
	Risk of schizophrenia in people with coeliac disease, ulcerative colitis and Crohn's disease: a general population-based study. J West, RF Logan, RB Hubbard, TR Card, Aliment Pharmacol Ther. 2006 Jan 1:71-4
	T cells in peripheral blood after gluten challenge in coeliac disease. RP Anderson, DA van Heel, JA Tye-Din, M Barnardo, M Salio, DP Jewell, AV Hill, Gut. 2005 Sep:1217-23
	The Canadian Celiac Health Survey. A Cranney, M Zarkadas, ID Graham, JD Butzner, M Rashid, R Warren, M Molloy, S Case, V Burrows, C Switzer, Dig Dis Sci. 2007 Apr:1087-95
	The value of double-balloon enteroscopy in patients with refractory celiac disease. M Hadithi, A Al-toma, J Oudejans, AA van Bodegraven, CJ Mulder, M Jacobs, Am J Gastroenterol. 2007 May:987-96
Supplementary evidence:
	American Gastroenterological Association medical position statement: short bowel syndrome and intestinal transplantation. American Gastroenterological Association, Gastroenterology. 2003 Apr:1105-10
	Bone resorption is decreased postprandially by intestinal factors and glucagon-like peptide-2 is a possible candidate. JJ Holst, B Hartmann, IB Gottschalck, PB Jeppesen, J Miholic, DB Henriksen, Scand J Gastroenterol. 2007 Jul:814-20
	Celiac disease: Working Group Report of the First World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition. ID Hill, S Bhatnagar, DJ Cameron, S De Rosa, M Maki, GJ Russell, R Troncone, J Pediatr Gastroenterol Nutr. 2002:S78-88
	Chronic diarrhea and malabsorption (including short gut syndrome): Working Group Report of the First World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition. J Walker-Smith, J Barnard, Z Bhutta, J Heubi, Z Reeves, J Schmitz, J Pediatr Gastroenterol Nutr. 2002:S98-105
	Consumption of gluten-free products: should the threshold value for trace amounts of gluten be at 20, 100 or 200 p.p.m.? A Gibert, M Espadaler, M Angel Canela, A Sánchez, C Vaqué, M Rafecas, Eur J Gastroenterol Hepatol. 2006 Nov:1187-95
	Dietary guidelines and implementation for celiac disease. C Kupper, Gastroenterology. 2005 Apr:S121-7
	Eosinophilic oesophagitis and coeliac disease: is there an association? L Quaglietta, P Coccorullo, E Miele, F Pascarella, R Troncone, A Staiano, Aliment Pharmacol Ther. 2007 Aug 1:487-93
	Gliadin, glutenin or both? The search for the Holy Grail in coeliac disease. PD Howdle, Eur J Gastroenterol Hepatol. 2006 Jul:703-6
	Guideline for diagnosis of celiac disease. A Quisel, JM Gill, D Westerberg, Del Med J. 2002 May:229-41
	Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. ID Hill, MH Dirks, GS Liptak, RB Colletti, A Fasano, S Guandalini, EJ Hoffenberg, K Horvath, JA Murray, M Pivor, EG Seidman, North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, J Pediatr Gastroenterol Nutr. 2005 Jan:1-19
	Health-related quality of life in adult coeliac disease in Germany: results of a national survey. W Hæuser, J Gold, J Stein, WF Caspary, A Stallmach, Eur J Gastroenterol Hepatol. 2006 Jul:747-54
	Iron deficiency anaemia: are the British Society of Gastroenterology guidelines being adhered to? RN Patterson, SD Johnston, Postgrad Med J. 2003 Apr:226-8
	Meta and pooled analysis of European coeliac disease data. MC Babron, S Nilsson, S Adamovic, AT Naluai, J Wahlstr&oeig;m, H Ascher, PJ Ciclitira, LM Sollid, J Partanen, L Greco, F Clerget-Darpoux, European Genetics Cluster on Coeliac Disease, Eur J Hum Genet. 2003 Nov:828-34
	National Institutes of Health Consensus Development Conference Statement on Celiac Disease, June 28-30, 2004. [No Authors Listed], Gastroenterology. 2005 Apr:S1-9
	Nutritional management of the gluten-free diet in young people with celiac disease in The Netherlands. EG Hopman, S le Cessie, BM von Blomberg, ML Mearin, J Pediatr Gastroenterol Nutr. 2006 Jul:102-8
	Overweight in celiac disease: prevalence, clinical characteristics, and effect of a gluten-free diet. W Dickey, N Kearney, Am J Gastroenterol. 2006 Oct:2356-9
	Systematic review: the liver in coeliac disease. JM Duggan, AE Duggan, Aliment Pharmacol Ther. 2005 Mar 1:515-8
	The diagnostic accuracy of serologic tests for celiac disease: a systematic review. A Rostom, C Dubé, A Cranney, N Saloojee, R Sy, C Garritty, M Sampson, L Zhang, F Yazdi, V Mamaladze, I Pan, J MacNeil, D Mack, D Patel, D Moher, Gastroenterology. 2005 Apr:S38-46
	The Pediatric Association recommends: Oats can be implemented in the gluten-free diet L Stenhammar, L H&oeig;gberg, R Saalman, Lakartidningen. 2004 Apr 29:1610-1
	The prevalence of celiac disease in average-risk and at-risk Western European populations: a systematic review. C Dubé, A Rostom, R Sy, A Cranney, N Saloojee, C Garritty, M Sampson, L Zhang, F Yazdi, V Mamaladze, I Pan, J Macneil, D Mack, D Patel, D Moher, Gastroenterology. 2005 Apr:S57-67