WGO Graded Evidence: Management of Ascites Complicating Cirrhosis in Adults

Level: Clinical Trials: 16 Abstracts

Legend:   : Special Mention  : Important  : Very Important  : Key Development
	Effects of clonidine on diuretic response in ascitic patients with cirrhosis and activation of sympathetic nervous system. A Lenaerts, T Codden, JC Meunier, JP Henry, G Ligny, Hepatology. 2006 Oct:844-9
	Oral V2 receptor antagonist (RWJ-351647) in patients with cirrhosis and ascites: a randomized, double-blind, placebo-controlled, single ascending dose study. PJ Thuluvath, A Maheshwari, F Wong, HW Yoo, RW Schrier, C Parikh, S Steare, J Korula, Aliment Pharmacol Ther. 2006 Sep 15:973-82
	Terlipressin versus albumin in paracentesis-induced circulatory dysfunction in cirrhosis: a randomized study. V Singh, R Kumar, CK Nain, B Singh, AK Sharma, J Gastroenterol Hepatol. 2006 Jan:303-7
Supplementary evidence:
	Clinical and neurohumoral response to posture, physical exercise, and ascites treatment in Child-Pugh C liver cirrhosis: randomized prospective trial. V Degoricija, V Zjacic-Rotkvic, J Marout, S Sefer, B Troskot, Croat Med J. 2003 Apr:178-86
	Clinical observation of effect of xiao gu san on cirrhosis ascites YX Sun, C Liu, Zhongguo Zhong Yao Za Zhi. 2004 Oct:993-5
	Comparison of the effect of terlipressin and albumin on arterial blood volume in patients with cirrhosis and tense ascites treated by paracentesis: a randomised pilot study. R Moreau, T Asselah, B Condat, C de Kerguenec, F Pessione, B Bernard, T Poynard, M Binn, JD Grangé, D Valla, D Lebrec, Gut. 2002 Jan:90-4
	Effects of celecoxib and naproxen on renal function in nonazotemic patients with cirrhosis and ascites. J Clària, JD Kent, M López-Parra, G Escolar, L Ruiz-Del-Arbol, P Ginès, W Jiménez, B Vucelic, V Arroyo, Hepatology. 2005 Mar:579-87
	Efficacy and safety of large volume paracentesis in cirrhotic patients with spontaneous bacterial peritonitis: a randomized prospective study CH Choi, KH Han, do Y Kim, JH Cho, JY Cheong, KH Song, CY Chon, YM Moon, Taehan Kan Hakhoe Chi. 2002 Mar:52-60
	Intraperitoneal chemotherapy with mitoxantrone in malignant ascites. KH Link, M Roitman, M Holtappels, I Runnebaum, H Urbanzyk, G Leder, L Staib, Surg Oncol Clin N Am. 2003 Jul:865-72, xvi-xvii
	Nadolol is superior to isosorbide mononitrate for the prevention of the first variceal bleeding in cirrhotic patients with ascites. G Borroni, F Salerno, M Cazzaniga, F Bissoli, E Lorenzano, A Maggi, S Visentin, A Panzeri, R de Franchis, J Hepatol. 2002 Sep:315-21
	Randomized controlled study of TIPS versus paracentesis plus albumin in cirrhosis with severe ascites. F Salerno, M Merli, O Riggio, M Cazzaniga, V Valeriano, M Pozzi, A Nicolini, F Salvatori, Hepatology. 2004 Sep:629-35
	Randomized trial comparing albumin and saline in the prevention of paracentesis-induced circulatory dysfunction in cirrhotic patients with ascites. J Sola-Vera, J Miñana, E Ricart, M Planella, B González, X Torras, J Rodríguez, J Such, S Pascual, G Soriano, M Pérez-Mateo, C Guarner, Hepatology. 2003 May:1147-53
	Spironolactone alone or in combination with furosemide in the treatment of moderate ascites in nonazotemic cirrhosis. A randomized comparative study of efficacy and safety. J Santos, R Planas, A Pardo, R Durández, E Cabré, RM Morillas, ML Granada, JA Jiménez, E Quintero, MA Gassull, J Hepatol. 2003 Aug:187-92
	TIPS versus peritoneovenous shunt in the treatment of medically intractable ascites: a prospective randomized trial. AS Rosemurgy, EE Zervos, WC Clark, DP Thometz, TJ Black, BR Zwiebel, BT Kudryk, LS Grundy, LC Carey, Ann Surg. 2004 Jun:883-9; discussion 889-91
	Transjugular intrahepatic portosystemic shunting versus paracentesis plus albumin for refractory ascites in cirrhosis. P Ginès, J Uriz, B Calahorra, G Garcia-Tsao, PS Kamath, LR Del Arbol, R Planas, J Bosch, V Arroyo, J Rodés, Gastroenterology. 2002 Dec:1839-47
	Treatment of cirrhotic tense ascites with Dextran-40 versus albumin associated with large volume paracentesis: a randomized controlled trial. D García-Compean, P Blanc, D Larrey, JP Daures, J Hirtz, E Mendoza, H Maldonado, H Michel, Ann Hepatol. 2002 Jan-Mar:29-35