Legend: : Special Mention  : Important : Very Important : Key Development |
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A randomized controlled trial comparing ligation and sclerotherapy as emergency endoscopic treatment added to somatostatin in acute variceal bleeding.
C Villanueva, M Piqueras, C Aracil, C Gómez, JM López-Balaguer, B Gonzalez, A Gallego, X Torras, G Soriano, S Sáinz, S Benito, J Balanzó, J Hepatol. 2006 Oct:560-7 |
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Acute hemodynamic effects of octreotide and terlipressin in patients with cirrhosis: a randomized comparison.
SK Baik, PH Jeong, SW Ji, BS Yoo, HS Kim, DK Lee, SO Kwon, YJ Kim, JW Park, SJ Chang, SS Lee, Am J Gastroenterol. 2005 Mar:631-5 |
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Randomized study comparing banding and propranolol to prevent initial variceal hemorrhage in cirrhotics with high-risk esophageal varices.
R Jutabha, DM Jensen, P Martin, T Savides, SH Han, J Gornbein, Gastroenterology. 2005 Apr:870-81 |
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A randomized trial of endoscopic treatment of acute gastric variceal hemorrhage: N-butyl-2-cyanoacrylate injection versus band ligation.
PC Tan, MC Hou, HC Lin, TT Liu, FY Lee, FY Chang, SD Lee, Hepatology. 2006 Apr:690-7 |
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Distal splenorenal shunt versus transjugular intrahepatic portal systematic shunt for variceal bleeding: a randomized trial.
JM Henderson, TD Boyer, MH Kutner, JR Galloway, LF Rikkers, LJ Jeffers, K Abu-Elmagd, J Connor, DIVERT Study Group, Gastroenterology. 2006 May:1643-51 |
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Endoscopic variceal ligation plus propranolol versus endoscopic variceal ligation alone in primary prophylaxis of variceal bleeding.
SK Sarin, M Wadhawan, SR Agarwal, P Tyagi, BC Sharma, Am J Gastroenterol. 2005 Apr:797-804 |
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Endoscopic variceal ligation versus propranolol in prophylaxis of first variceal bleeding in patients with cirrhosis.
CS Lay, YT Tsai, FY Lee, YL Lai, CJ Yu, CB Chen, CY Peng, J Gastroenterol Hepatol. 2006 Feb:413-9 |
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Endoscopic variceal ligation vs. propranolol for prevention of first variceal bleeding: a randomized controlled trial.
D Psilopoulos, P Galanis, S Goulas, IS Papanikolaou, I Elefsiniotis, C Liatsos, L Sparos, C Mavrogiannis, Eur J Gastroenterol Hepatol. 2005 Oct:1111-7 |
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Hemodynamic effects of terlipressin and high somatostatin dose during acute variceal bleeding in nonresponders to the usual somatostatin dose.
C Villanueva, M Planella, C Aracil, JM López-Balaguer, B González, J Miñana, J Balanzó, Am J Gastroenterol. 2005 Mar:624-30 |
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Inhibition of transient lower esophageal sphincter relaxation and gastroesophageal reflux by metabotropic glutamate receptor ligands.
CL Frisby, JP Mattsson, JM Jensen, A Lehmann, J Dent, LA Blackshaw, Gastroenterology. 2005 Sep:995-1004 |
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Primary prophylaxis against variceal bleeding: beta-blockers, endoscopic ligation, or both?
N Chalasani, TD Boyer, Am J Gastroenterol. 2005 Apr:805-7 |
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Treatment of esophageal varices: a randomized controlled trial comparing endoscopic sclerotherapy and EUS-guided sclerotherapy of esophageal collateral veins.
GA de Paulo, JC Ardengh, FS Nakao, AP Ferrari, Gastrointest Endosc. 2006 Mar:396-402; quiz 463 |
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Ultrasound system to measure esophageal varix pressure: an in vitro validation study.
JL Puckett, J Liu, V Bhalla, D Kravetz, ML Krinsky, T Hassanein, RK Mittal, Am J Physiol Gastrointest Liver Physiol. 2005 May:G914-9 |
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A randomized control trial of bi-monthly versus bi-weekly endoscopic variceal ligation of esophageal varices.
H Yoshida, Y Mamada, N Taniai, K Yamamoto, Y Kawano, Y Mizuguchi, T Shimizu, T Takahashi, T Tajiri, Am J Gastroenterol. 2005 Sep:2005-9 |
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An evaluation of emergency sclerotherapy of varices in randomized trials: looking the needle in the eye.
CK Triantos, J Goulis, D Patch, GV Papatheodoridis, G Leandro, D Samonakis, E Cholongitas, AK Burroughs, Endoscopy. 2006 Aug:797-807 |
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Comparative study between nadolol and 5-isosorbide mononitrate vs. endoscopic band ligation plus sclerotherapy in the prevention of variceal rebleeding in cirrhotic patients: a randomized controlled t
G Romero, D Kravetz, J Argonz, C Vulcano, A Suarez, E Fassio, N Dominguez, A Bosco, A Muñoz, P Salgado, R Terg, Aliment Pharmacol Ther. 2006 Aug 15:601-11 |
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Endoscopic ligation vs. sclerotherapy in adults with extrahepatic portal venous obstruction: a prospective randomized study.
SA Zargar, G Javid, BA Khan, OJ Shah, GN Yattoo, AH Shah, GM Gulzar, J Singh, NA Shah, HM Shafi, Gastrointest Endosc. 2005 Jan:58-66 |
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Endoscopic outcome beyond esophageal variceal eradication in children with extrahepatic portal venous obstruction.
S Itha, SK Yachha, J Pediatr Gastroenterol Nutr. 2006 Feb:196-200 |
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Hemorheology in patients with liver cirrhosis: special emphasis on its relation to severity of esophageal variceal bleeding.
TT Liu, WJ Wong, MC Hou, HC Lin, FY Chang, SD Lee, J Gastroenterol Hepatol. 2006 May:908-13 |
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The prevalence and risk factors associated with esophageal varices in subjects with hepatitis C and advanced fibrosis.
AJ Sanyal, RJ Fontana, AM Di Bisceglie, JE Everhart, MC Doherty, GT Everson, JA Donovan, PF Malet, S Mehta, MY Sheikh, AE Reid, MG Ghany, DR Gretch, Halt-C Trial Group, Gastrointest Endosc. 2006 Dec:855-64 |
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A placebo-controlled clinical trial of nadolol in the prophylaxis of growth of small esophageal varices in cirrhosis.
C Merkel, R Marin, P Angeli, P Zanella, M Felder, E Bernardinello, G Cavallarin, M Bolognesi, C Donada, B Bellini, P Torboli, A Gatta, Gruppo Triveneto per l'Ipertensione Portale, Gastroenterology. 2004 Aug:476-84 |
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A randomized controlled trial of beta-blockers versus endoscopic band ligation for primary prophylaxis: a large sample size is required to show a difference in bleeding rates.
PJ Thuluvath, A Maheshwari, S Jagannath, A Arepally, Dig Dis Sci. 2005 Feb:407-10 |
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A randomized controlled trial of cyanoacrylate versus alcohol injection in patients with isolated fundic varices.
SK Sarin, AK Jain, M Jain, R Gupta, Am J Gastroenterol. 2002 Apr:1010-5 |
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A randomized, controlled trial of medical therapy versus endoscopic ligation for the prevention of variceal rebleeding in patients with cirrhosis.
D Patch, CA Sabin, J Goulis, G Gerunda, L Greenslade, C Merkel, AK Burroughs, Gastroenterology. 2002 Oct:1013-9 |
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Antibiotic prophylaxis after endoscopic therapy prevents rebleeding in acute variceal hemorrhage: a randomized trial.
MC Hou, HC Lin, TT Liu, BI Kuo, FY Lee, FY Chang, SD Lee, Hepatology. 2004 Mar:746-53 |
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Argon plasma coagulation prevents variceal recurrence after band ligation of esophageal varices: preliminary results of a prospective randomized trial.
L Cipolletta, MA Bianco, G Rotondano, R Marmo, C Meucci, R Piscopo, Gastrointest Endosc. 2002 Oct:467-71 |
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Banding ligation versus nadolol and isosorbide mononitrate for the prevention of esophageal variceal rebleeding.
GH Lo, WC Chen, MH Chen, PI Hsu, CK Lin, WL Tsai, KH Lai, Gastroenterology. 2002 Sep:728-34 |
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Comparison of the efficacy of octreotide, vasopressin, and omeprazole in the control of acute bleeding in patients with portal hypertensive gastropathy: a controlled study.
Y Zhou, L Qiao, J Wu, H Hu, C Xu, J Gastroenterol Hepatol. 2002 Sep:973-9 |
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Detachable endoloop vs. elastic band ligation for bleeding esophageal varices.
MI Naga, HH Okasha, AR Foda, MS Gomaa, AM Fouad, AG Masoud, HH El-din, Gastrointest Endosc. 2004 Jun:804-9 |
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Early increase of lower oesophageal sphincter pressure after band ligation of oesophageal varices in cirrhotics: an intriguing phenomenon.
A Avgerinos, N Viazis, A Armonis, J Vlachogiannakos, G Rekoumis, G Stefanidis, N Papadimitriou, S Manolakopoulos, SA Raptis, Eur J Gastroenterol Hepatol. 2002 Dec:1319-23 |
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Effects of endoscopic variceal treatment on oesophageal function: a prospective, randomized study.
N Viazis, A Armonis, J Vlachogiannakos, G Rekoumis, G Stefanidis, N Papadimitriou, S Manolakopoulos, A Avgerinos, Eur J Gastroenterol Hepatol. 2002 Mar:263-9 |
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Efficacy and safety of balloon-occluded endoscopic injection sclerotherapy as a prophylactic treatment for high-risk gastric fundal varices: a prospective, randomized, comparative clinical trial.
M Shiba, K Higuchi, K Nakamura, A Itani, T Kuga, H Okazaki, Y Fujiwara, T Arakawa, Gastrointest Endosc. 2002 Oct:522-8 |
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Endoscopic histoacryl obliteration vs. propranolol in the prevention of esophagogastric variceal rebleeding: a randomized trial.
S Evrard, JM Dumonceau, M Delhaye, P Golstein, J Devière, O Le Moine, Endoscopy. 2003 Sep:729-35 |
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Endoscopic ligation compared with sclerotherapy for bleeding esophageal varices in children with extrahepatic portal venous obstruction.
SA Zargar, G Javid, BA Khan, GN Yattoo, AH Shah, GM Gulzar, J Singh, BU Rehman, Z Din, Hepatology. 2002 Sep:666-72 |
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Endoscopic variceal ligation plus propranolol vs. transjugular intrahepatic portosystemic stent shunt: a long-term randomized trial.
P Sauer, J Hansmann, GM Richter, W Stremmel, A Stiehl, Endoscopy. 2002 Sep:690-7 |
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Influence of portal hypertension and its early decompression by TIPS placement on the outcome of variceal bleeding.
A Monescillo, F Martínez-Lagares, L Ruiz-del-Arbol, A Sierra, C Guevara, E Jiménez, JM Marrero, E Buceta, J Sánchez, A Castellot, M Peñate, A Cruz, E Peña, Hepatology. 2004 Oct:793-801 |
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Ligation versus propranolol for the primary prophylaxis of variceal bleeding in cirrhosis.
M Schepke, G Kleber, D Nurnberg, J Willert, L Koch, W Veltzke-Schlieker, C Hellerbrand, J Kuth, S Schanz, S Kahl, WE Fleig, T Sauerbruch, German Study Group for the Primary Prophylaxis of Variceal Bleeding, Hepatology. 2004 Jul:65-72 |
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Nadolol plus spironolactone in the prophylaxis of first variceal bleed in nonascitic cirrhotic patients: A preliminary study.
R Abecasis, D Kravetz, E Fassio, B Ameigeiras, D Garcia, R Isla, G Landeira, N Dominguez, G Romero, J Argonz, R Terg, Hepatology. 2003 Feb:359-65 |
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Pantoprazole reduces the size of postbanding ulcers after variceal band ligation: a randomized, controlled trial.
NJ Shaheen, E Stuart, SM Schmitz, KL Mitchell, MW Fried, S Zacks, MW Russo, J Galanko, R Shrestha, Hepatology. 2005 Mar:588-94 |
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Primary prophylaxis of variceal hemorrhage: a randomized controlled trial comparing band ligation, propranolol, and isosorbide mononitrate.
HF Lui, AJ Stanley, EH Forrest, R Jalan, WS Hislop, PR Mills, ND Finlayson, AJ Macgilchrist, PC Hayes, Gastroenterology. 2002 Sep:735-44 |
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Propranolol alone may not be acceptable to prevent first esophageal variceal bleeding in Japanese cirrhotic patients: randomized controlled trial.
M Tomikawa, R Shimabukuro, K Okita, N Tsutsumi, T Akahoshi, M Hashizume, K Sugimachi, J Gastroenterol Hepatol. 2004 May:576-81 |
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Propranolol for the prevention of first esophageal variceal hemorrhage: a lifetime commitment?
DR Abraczinskas, R Ookubo, ND Grace, RJ Groszmann, J Bosch, G Garcia-Tsao, CR Richardson, DS Matloff, J Rodés, HO Conn, Hepatology. 2001 Dec:1096-102 |
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Propranolol plus placebo versus propranolol plus isosorbide-5-mononitrate in the prevention of a first variceal bleed: a double-blind RCT.
JC García-Pagán, R Morillas, R Bañares, A Albillos, C Villanueva, C Vila, J Genescà, M Jimenez, M Rodriguez, JL Calleja, J Balanzó, F García-Durán, R Planas, J Bosch, Spanish Variceal Bleeding Study Group, Hepatology. 2003 Jun:1260-6 |
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Randomised controlled trial of long term portographic follow up versus variceal band ligation following transjugular intrahepatic portosystemic stent shunt for preventing oesophageal variceal rebleedi
D Tripathi, HF Lui, A Helmy, K Dabos, E Forrest, AJ Stanley, R Jalan, DN Redhead, PC Hayes, Gut. 2004 Mar:431-7 |
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Transjugular intrahepatic portosystemic shunting is not superior to endoscopic variceal band ligation for prevention of variceal rebleeding in cirrhotic patients: a randomized, controlled trial.
V Gulberg, M Schepke, G Geigenberger, J Holl, KA Brensing, T Waggershauser, M Reiser, HH Schild, T Sauerbruch, AL Gerbes, Scand J Gastroenterol. 2002 Mar:338-43 |
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Variceal ligation plus nadolol compared with ligation for prophylaxis of variceal rebleeding: a multicenter trial.
J de la Peña, E Brullet, E Sanchez-Hernández, M Rivero, M Vergara, JL Martin-Lorente, C Garcia Suárez, Hepatology. 2005 Mar:572-8 |