WGO Graded Evidence: Inflammatory Bowel Disease

Level: Cascade and Global Epidemiology: 6 Abstract

Legend:   : Special Mention  : Important  : Very Important  : Key Development
	World Gastroenterology Organization Practice Guidelines for the diagnosis andmanagement of IBD in 2010. Bernstein CN, Fried M, Krabshuis JH, Cohen H, Eliakim R, Fedail S, Gearry R, Goh KL, Hamid S, Khan AG, LeMair AW, Malfertheiner, Ouyang Q, Rey JF, Sood A,Steinwurz F, Thomsen OO, Thomson A, Watermeyer G., Inflamm Bowel Dis. 2010 Jan;16(1):112-24.
	Ulcerative colitis and pregnancy outcomes in an Asian population. Lin HC, Chiu CC, Chen SF, Lou HY, Chiu WT, Chen YH., Am J Gastroenterol. 2010 Feb;105(2):387-94. Epub 2009 Oct 6.
	NOD2 mutations and anti-Saccharomyces cerevisiae antibodies are risk factors for Crohn's disease in African Americans. Dassopoulos T, Nguyen GC, Talor MV, Datta LW, Isaacs KL, Lewis JD, Gold MS,Valentine JF, Smoot DT, Harris ML, Oliva-Hemker M, Bayless TM; NIDDK IBD GeneticsConsortium, Burek CL, Brant SR., Am J Gastroenterol. 2010 Feb;105(2):378-86. Epub 2009 Oct 13.
	What determines the later clinical course of patients who do not undergocolectomy at the first attack? A Japanese cohort study on ulcerative colitis. Shiga H, Takagi S, Inoue R, Kinouchi Y, Ohkubo T, Takahashi S, Negoro K, YokoyamaH, Kato S, Fukushima K, Hiwatashi N, Shimosegawa T., Digestion. 2010;81(2):104-12.
	Efficacy and safety of pulse steroid therapy in Japanese pediatric patients with ulcerative colitis: a survey of the Japanese Society for Pediatric InflammatoryBowel Disease. Nagata S, Shimizu T, Kudo T, Tomomasa T, Tajiri H, Yoden A, Kagimoto S, Tahara T,Ushijima K, Uchida K, Kobayashi A., Digestion. 2010;81(3):188-92. Epub 2010 Jan 19.
Supplementary evidence:
	Down-regulation of protein and mRNA expression of IL-8 and ICAM-1 in colon tissue of ulcerative colitis patients by partition-herb moxibustion. Zhou EH, Liu HR, Wu HG, Shi Z, Zhang W, Zhu Y, Shi DR, Zhou S, Dig Dis Sci. 2009 Oct;54(10):2198-206