WGO Graded Evidence: Obesity

Level: Other Reading: 23 Abstracts

Legend:   : Special Mention  : Important  : Very Important  : Key Development
	A 52-year-old woman with obesity: review of bariatric surgery. Wee CC, JAMA. 2009 Sep 9;302(10):1097-104
	Bariatric surgery and taste: novel mechanisms of weight loss. Miras AD, le Roux CW., Curr Opin Gastroenterol. 2010 Mar;26(2):140-5.
	Dietary fiber supplements: effects in obesity and metabolic syndrome andrelationship to gastrointestinal functions. Papathanasopoulos A, Camilleri M., Gastroenterology. 2010 Jan;138(1):65-72.e1-2. Epub 2009 Nov 18.
	Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weightyconnection. Starley BQ, Calcagno CJ, Harrison SA., Hepatology. 2010 May;51(5):1820-32.
	Dietary fiber supplements: effects in obesity and metabolic syndrome and relationship to gastrointestinal functions. Papathanasopoulos A, Camilleri M, Gastroenterology. 2010 Jan;138(1):65-72.e1-2
	Perioperative safety in the longitudinal assessment of bariatric surgery. Longitudinal Assessment of Bariatric Surgery (LABS) Consortium, Flum DR, Belle SH, King WC, Wahed AS, Berk P, Chapman W, Pories W, Courcoulas A, McCloskey C, Mitchell J, Patterson E, Pomp A, Staten MA, Yanovski SZ, Thirlby R, Wolfe B, N Engl J Med. 2009 Jul 30;361(5):445-54
	Endoscopic options for the treatment of obesity. Ibrahim M, Blero D, Deviere J., Gastroenterology. 2010 Jun;138(7):2228-32, 2232.e1. Epub 2010 Apr 21.
	Genomics, type 2 diabetes, and obesity. McCarthy MI., N Engl J Med. 2010 Dec 9;363(24):2339-50.
	Fitness versus fatness: moving beyond weight loss in nonalcoholic fatty liverdisease. Johnson NA, George J., Hepatology. 2010 Jul;52(1):370-81.
	Lipid-induced insulin resistance: unravelling the mechanism. Samuel VT, Petersen KF, Shulman GI., Lancet. 2010 Jun 26;375(9733):2267-77.
	Role of diet in the development of inflammatory bowel disease. Chapman-Kiddell CA, Davies PS, Gillen L, Radford-Smith GL., Inflamm Bowel Dis. 2010 Jan;16(1):137-51.
	Obesity and the human microbiome. Ley RE., Curr Opin Gastroenterol. 2010 Jan;26(1):5-11.
	Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, andclinical implications. Fabbrini E, Sullivan S, Klein S., Hepatology. 2010 Feb;51(2):679-89.
	Emerging technology: endoluminal treatment of obesity. Coté GA, Edmundowicz SA, Gastrointest Endosc. 2009 Nov;70(5):991-9
	Aerobic exercise training reduces hepatic and visceral lipids in obese individuals without weight loss. Johnson NA, Sachinwalla T, Walton DW, Smith K, Armstrong A, Thompson MW, George J, Hepatology. 2009 Oct;50(4):1105-12
	Interactions between gut microbiota and host metabolism predisposing to obesityand diabetes. Musso G, Gambino R, Cassader M., Annu Rev Med. 2011 Feb 18;62:361-80.
	Visceral obesity and the risk of Barrett's esophagus. Akiyama T, Yoneda M, Maeda S, Nakajima A, Koyama S, Inamori M., Digestion. 2011;83(3):142-5. Epub 2011 Jan 21.
	Waist circumference predicts increased complications in rectal cancer surgery. Balentine CJ, Robinson CN, Marshall CR, Wilks J, Buitrago W, Haderxhanaj K,Sansgiry S, Petersen NJ, Bansal V, Albo D, Berger DH., J Gastrointest Surg. 2010 Nov;14(11):1669-79. Epub 2010 Sep 11.
	Endoscopic management in the bariatric surgical patient. Levitzky BE, Wassef WY., Curr Opin Gastroenterol. 2010 Nov;26(6):632-9.
	Biological mechanisms linking obesity and cancer risk: new perspectives. Roberts DL, Dive C, Renehan AG., Annu Rev Med. 2010;61:301-16.
	Childhood obesity. Han JC, Lawlor DA, Kimm SY., Lancet. 2010 May 15;375(9727):1737-48. Epub 2010 May 5.
Supplementary evidence:
	Surgical treatment of obesity. Ward M, Prachand V, Gastrointest Endosc. 2009 Nov;70(5):985-90
	A cohort study of the effect of alcohol consumption and obesity on serum liver enzyme levels. Shen Z, Li Y, Yu C, Shen Y, Xu L, Xu C, Xu G, Eur J Gastroenterol Hepatol. 2009 Oct 13;