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World Gastroenterology Organisation
World Gastroenterology Organisation
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Acute Diarrhea in Adults

Level: Clinical Trials: 15 Abstracts

Legend: : Key Development,  : Very Important,  : Important, [no star]: Special Mention

Probiotics for treatment of acute diarrhoea in children: randomised clinical trial of five different preparations.
Canani RB, Cirillo P, Terrin G, Cesarano L, Spagnuolo MI, De Vincenzo A, Albano F, Passariello A, De Marco G, Manguso F, Guarino A, BMJ. 2007 Aug 18;335(7615):340

Amylase-resistant starch as adjunct to oral rehydration therapy in children with diarrhea.
Raghupathy P, Ramakrishna BS, Oommen SP, Ahmed MS, Priyaa G, Dziura J, Young GP, Binder HJ, J Pediatr Gastroenterol Nutr. 2006 Apr;42(4):362-8

Effect of handwashing on child health: a randomised controlled trial.
Luby SP, Agboatwalla M, Feikin DR, Painter J, Billhimer W, Altaf A, Hoekstra RM, Lancet. 2005 Jul 16-22;366(9481):225-33

A blind, randomized comparison of racecadotril and loperamide for stopping acute diarrhea in adults.
Wang HH, Shieh MJ, Liao KF, World J Gastroenterol. 2005 Mar 14;11(10):1540-3

Saccharomyces boulardii in the prevention of antibiotic-associated diarrhoea in children: a randomized double-blind placebo-controlled trial.
Kotowska M, Albrecht P, Szajewska H, Aliment Pharmacol Ther. 2005 Mar 1;21(5):583-90

Effects of long-term consumption of a fermented infant formula (with Bifidobacterium breve c50 and Streptococcus thermophilus 065) on acute diarrhea in healthy infants.
Thibault H, Aubert-Jacquin C, Goulet O, J Pediatr Gastroenterol Nutr. 2004 Aug;39(2):147-52


Phase III, double-blind study of depot octreotide versus placebo in the prevention of acute diarrhea in patients receiving pelvic radiation therapy: results of North Central Cancer Treatment Group N00CA.
Martenson JA, Halyard MY, Sloan JA, Proulx GM, Miller RC, Deming RL, Dick SJ, Johnson HA, Tai TH, Zhu AW, Keit J, Stien KJ, Atherton PJ, J Clin Oncol. 2008 Nov 10;26(32):5248-53


Loperamide plus azithromycin more effectively treats travelers' diarrhea in Mexico than azithromycin alone.
Ericsson CD, DuPont HL, Okhuysen PC, Jiang ZD, DuPont MW, J Travel Med. 2007 Sep-Oct;14(5):312-9


The effect of early nutritional supplementation with a mixture of probiotic, prebiotic, fiber and micronutrients in infants with acute diarrhea in Indonesia.
Agustina R, Lukito W, Firmansyah A, Suhardjo HN, Murniati D, Bindels J, Asia Pac J Clin Nutr. 2007;16(3):435-42


Efficacy of rice-based oral rehydration solution containing recombinant human lactoferrin and lysozyme in Peruvian children with acute diarrhea.
Zavaleta N, Figueroa D, Rivera J, Sánchez J, Alfaro S, Lönnerdal B, J Pediatr Gastroenterol Nutr. 2007 Feb;44(2):258-64


Randomized control trial of live Lactobacillus acidophilus plus Bifidobacterium infantis in treatment of infantile acute watery diarrhea.
Vivatvakin B, Kowitdamrong E, J Med Assoc Thai. 2006 Sep;89 Suppl 3:S126-33


Zinc supplementation in acute diarrhea is acceptable, does not interfere with oral rehydration, and reduces the use of other medications: a randomized trial in five countries.
Awasthi S, INCLEN Childnet Zinc Effectiveness for Diarrhea (IC-ZED) Group, J Pediatr Gastroenterol Nutr. 2006 Mar;42(3):300-5


Validation of a single concentration methacholine inhalation provocation test (SCIPT) in children.
Hagmolen of ten Have W, van den Berg NJ, van der Palen J, Bindels PJ, van Aalderen WM, J Asthma. 2005 Jul-Aug;42(6):419-23


Gabapentin reduces rectal mechanosensitivity and increases rectal compliance in patients with diarrhoea-predominant irritable bowel syndrome.
Lee KJ, Kim JH, Cho SW, Aliment Pharmacol Ther. 2005 Nov 15;22(10):981-8


Failure of dietary oligofructose to prevent antibiotic-associated diarrhoea.
Lewis S, Burmeister S, Cohen S, Brazier J, Awasthi A, Aliment Pharmacol Ther. 2005 Feb 15;21(4):469-77