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Diverticular Disease

Level: Clinical Trials: 7 Abstracts

Legend: : Key Development,  : Very Important,  : Important, [no star]: Special Mention

   

Laparoscopic Lavage vs Primary Resection for Acute Perforated Diverticulitis: The SCANDIV Randomized Clinical Trial.
Schultz JK, Yaqub S, Wallon C, Blecic L, Forsmo HM, Folkesson J, Buchwald P, Körner H, Dahl FA, Øresland T; SCANDIV Study Group., JAMA. 2015 Oct 6;314(13):1364-75. doi: 10.1001/jama.2015.12076.

   

Laparoscopic peritoneal lavage or sigmoidectomy for perforated diverticulitis with purulent peritonitis: a multicentre, parallel-group, randomised, open-label trial.
Vennix S, Musters GD, Mulder IM, Swank HA, Consten EC, Belgers EH, van Geloven AA, Gerhards MF, Govaert MJ, van Grevenstein WM, Hoofwijk AG, Kruyt PM, Nienhuijs SW, Boermeester MA, Vermeulen J, van Dieren S, Lange JF, Bemelman WA; Ladies trial colloborators., Lancet. 2015 Sep 26;386(10000):1269-77. doi: 10.1016/S0140-6736(15)61168-0. Epub 2015 Jul 22.

 

Primary anastomosis vs. Hartmann's procedure in patients undergoing emergency left colectomy for perforated diverticulitis.
Zingg U, Pasternak I, Dietrich M, Seifert B, Oertli D, Metzger U, Colorectal Dis. 2008 Oct 1;

 

Association between the location of diverticular disease and the irritable bowel syndrome: a multicenter study in Japan.
Yamada E, Inamori M, Uchida E, Tanida E, Izumi M, Takeshita K, Fujii T, Komatsu K, Hamanaka J, Maeda S, Kanesaki A, Matsuhashi N, Nakajima A., Am J Gastroenterol. 2014 Dec;109(12):1900-5. doi: 10.1038/ajg.2014.323. Epub 2014 Oct 21.
Comments: Association between diverticulosis and IBS

 

Mesalamine did not prevent recurrent diverticulitis in phase 3 controlled trials.
Raskin JB, Kamm MA, Jamal MM, Márquez J, Melzer E, Schoen RE, Szalóki T, Barrett K, Streck P., Gastroenterology. 2014 Oct;147(4):793-802. doi: 10.1053/j.gastro.2014.07.004. Epub 2014 Jul 16.
Comments: Mesalamine does not prevent recurrent diverticulitis

        

Involvement of central immunity in uncomplicated diverticular disease.
Cianci R, Iacopini F, Petruzziello L, Cammarota G, Pandolfi F, Costamagna G, Scand J Gastroenterol. 2009;44(1):108-15

 

Continuous versus cyclic mesalazine therapy for patients affected by recurrent symptomatic uncomplicated diverticular disease of the colon.
A Tursi, G Brandimarte, GM Giorgetti, W Elisei, Dig Dis Sci. 2007 Mar:671-4

 

Interaction between rifaximin and dietary fibre in patients with diverticular disease.
R D'Incà, F Pomerri, MG Vettorato, E Dal Pont, V Di Leo, A Ferronato, V Medici, GC Sturniolo, Aliment Pharmacol Ther. 2007 Apr 1:771-9

 

Prevention of complications and symptomatic recurrences in diverticular disease with mesalazine: a 12-month follow-up.
G Comparato, L Fanigliulo, LG Cavallaro, G Aragona, GM Cavestro, V Iori, M Maino, G Mazzocchi, P Muzzetto, G Colla, M Sianesi, A Franzé, FD Mario, Dig Dis Sci. 2007 Nov:2934-41