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World Gastroenterology Organisation
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Treatment of Esophageal Varices

Level: Clinical Trials: 36 Abstracts

Legend: : Key Development,  : Very Important,  : Important, [no star]: Special Mention

   

Prevention of Rebleeding From Esophageal Varices in Patients With Cirrhosis Receiving Small-Diameter Stents Versus Hemodynamically Controlled Medical Therapy.
Sauerbruch T, Mengel M, Dollinger M, Zipprich A, Rössle M, Panther E, Wiest R, Caca K, Hoffmeister A, Lutz H, Schoo R, Lorenzen H, Trebicka J, Appenrodt B, Schepke M, Fimmers R; German Study Group for Prophylaxis of Variceal Rebleeding., Gastroenterology. 2015 Sep;149(3):660-8.e1. doi: 10.1053/j.gastro.2015.05.011. Epub 2015 May 16.

 

Terlipressin vs. octreotide in bleeding esophageal varices as an adjuvant therapy with endoscopic band ligation: a randomized double-blind placebo-controlled trial.
Abid S, Jafri W, Hamid S, Salih M, Azam Z, Mumtaz K, Shah HA, Abbas Z, Am J Gastroenterol. 2009 Mar;104(3):617-23

  

Impact of anticoagulation on upper-gastrointestinal bleeding in cirrhosis. A retrospective multicenter study.
Cerini F, Gonzalez JM, Torres F, Puente Á, Casas M, Vinaixa C, Berenguer M, Ardevol A, Augustin S, Llop E, Senosiaín M, Villanueva C, de la Peña J, Bañares R, Genescá J, Sopeña J, Albillos A, Bosch J, Hernández-Gea V, Garcia-Pagán JC., Hepatology. 2015 Aug;62(2):575-83. doi: 10.1002/hep.27783. Epub 2015 Apr 27.

 

Microwave coagulation versus sclerotherapy after band ligation to preventrecurrence of high risk of bleeding esophageal varices in Child-Pugh's A and B patients.
Monici LT, Meirelles-Santos JO, Soares EC, Mesquita MA, Zeitune JM, Montes CG, Almeida JR, Yamanaka A, Magna LA., J Gastroenterol. 2010 Feb;45(2):204-10. Epub 2009 Oct 3.

 

A randomized controlled trial comparing ligation and sclerotherapy as emergency endoscopic treatment added to somatostatin in acute variceal bleeding.
C Villanueva, M Piqueras, C Aracil, C Gómez, JM López-Balaguer, B Gonzalez, A Gallego, X Torras, G Soriano, S Sáinz, S Benito, J Balanzó, J Hepatol. 2006 Oct:560-7

 

Acute hemodynamic effects of octreotide and terlipressin in patients with cirrhosis: a randomized comparison.
SK Baik, PH Jeong, SW Ji, BS Yoo, HS Kim, DK Lee, SO Kwon, YJ Kim, JW Park, SJ Chang, SS Lee, Am J Gastroenterol. 2005 Mar:631-5

 

Randomized study comparing banding and propranolol to prevent initial variceal hemorrhage in cirrhotics with high-risk esophageal varices.
R Jutabha, DM Jensen, P Martin, T Savides, SH Han, J Gornbein, Gastroenterology. 2005 Apr:870-81

 

The predictors of the presence of varices in patients with primary sclerosingcholangitis.
Treeprasertsuk S, Kowdley KV, Luketic VA, Harrison ME, McCashland T, Befeler AS, Harnois D, Jorgensen R, Petz J, Keach J, Schmoll J, Hoskin T, Thapa P, Enders F, Lindor KD., Hepatology. 2010 Apr;51(4):1302-10.

 

A randomized trial of endoscopic treatment of acute gastric variceal hemorrhage: N-butyl-2-cyanoacrylate injection versus band ligation.
PC Tan, MC Hou, HC Lin, TT Liu, FY Lee, FY Chang, SD Lee, Hepatology. 2006 Apr:690-7

 

Distal splenorenal shunt versus transjugular intrahepatic portal systematic shunt for variceal bleeding: a randomized trial.
JM Henderson, TD Boyer, MH Kutner, JR Galloway, LF Rikkers, LJ Jeffers, K Abu-Elmagd, J Connor, DIVERT Study Group, Gastroenterology. 2006 May:1643-51

 

Endoscopic variceal ligation plus propranolol versus endoscopic variceal ligation alone in primary prophylaxis of variceal bleeding.
SK Sarin, M Wadhawan, SR Agarwal, P Tyagi, BC Sharma, Am J Gastroenterol. 2005 Apr:797-804

 

Endoscopic variceal ligation versus propranolol in prophylaxis of first variceal bleeding in patients with cirrhosis.
CS Lay, YT Tsai, FY Lee, YL Lai, CJ Yu, CB Chen, CY Peng, J Gastroenterol Hepatol. 2006 Feb:413-9

 

Endoscopic variceal ligation vs. propranolol for prevention of first variceal bleeding: a randomized controlled trial.
D Psilopoulos, P Galanis, S Goulas, IS Papanikolaou, I Elefsiniotis, C Liatsos, L Sparos, C Mavrogiannis, Eur J Gastroenterol Hepatol. 2005 Oct:1111-7

 

Hemodynamic effects of terlipressin and high somatostatin dose during acute variceal bleeding in nonresponders to the usual somatostatin dose.
C Villanueva, M Planella, C Aracil, JM López-Balaguer, B González, J Miñana, J Balanzó, Am J Gastroenterol. 2005 Mar:624-30

 

Inhibition of transient lower esophageal sphincter relaxation and gastroesophageal reflux by metabotropic glutamate receptor ligands.
CL Frisby, JP Mattsson, JM Jensen, A Lehmann, J Dent, LA Blackshaw, Gastroenterology. 2005 Sep:995-1004

 

Primary prophylaxis against variceal bleeding: beta-blockers, endoscopic ligation, or both?
N Chalasani, TD Boyer, Am J Gastroenterol. 2005 Apr:805-7

 

Treatment of esophageal varices: a randomized controlled trial comparing endoscopic sclerotherapy and EUS-guided sclerotherapy of esophageal collateral veins.
GA de Paulo, JC Ardengh, FS Nakao, AP Ferrari, Gastrointest Endosc. 2006 Mar:396-402; quiz 463

 

Ultrasound system to measure esophageal varix pressure: an in vitro validation study.
JL Puckett, J Liu, V Bhalla, D Kravetz, ML Krinsky, T Hassanein, RK Mittal, Am J Physiol Gastrointest Liver Physiol. 2005 May:G914-9

 

Emergency portacaval shunt versus rescue portacaval shunt in a randomized controlled trial of emergency treatment of acutely bleeding esophageal varices in cirrhosis--part 3.
Orloff MJ, Isenberg JI, Wheeler HO, Haynes KS, Jinich-Brook H, Rapier R, Vaida F, Hye RJ., J Gastrointest Surg. 2010 Nov;14(11):1782-95. Epub 2010 Jul 24.

 

A specialized, nurse-run titration clinic: a feasible option for optimizingbeta-blockade in non-clinical trial patients.
Tandon P, Saez R, Berzigotti A, Abraldes JG, Garcia-Pagan JC, Bosch J., Am J Gastroenterol. 2010 Sep;105(9):1917-21.

 

Direct Costs of Care in a Randomized Controlled Trial of Endoscopic Sclerotherapy versus Emergency Portacaval Shunt for Bleeding Esophageal Varices in Cirrhosis-Part 4.
Orloff MJ, Isenberg JI, Wheeler HO, Haynes KS, Jinich-Brook H, Rapier R, Vaida F, Hye RJ., J Gastrointest Surg. 2011 Jan;15(1):38-47. Epub 2010 Sep 8.

 

A randomized control trial of bi-monthly versus bi-weekly endoscopic variceal ligation of esophageal varices.
H Yoshida, Y Mamada, N Taniai, K Yamamoto, Y Kawano, Y Mizuguchi, T Shimizu, T Takahashi, T Tajiri, Am J Gastroenterol. 2005 Sep:2005-9

 

An evaluation of emergency sclerotherapy of varices in randomized trials: looking the needle in the eye.
CK Triantos, J Goulis, D Patch, GV Papatheodoridis, G Leandro, D Samonakis, E Cholongitas, AK Burroughs, Endoscopy. 2006 Aug:797-807

 

Comparative study between nadolol and 5-isosorbide mononitrate vs. endoscopic band ligation plus sclerotherapy in the prevention of variceal rebleeding in cirrhotic patients: a randomized controlled t
G Romero, D Kravetz, J Argonz, C Vulcano, A Suarez, E Fassio, N Dominguez, A Bosco, A Muñoz, P Salgado, R Terg, Aliment Pharmacol Ther. 2006 Aug 15:601-11

 

Endoscopic ligation vs. sclerotherapy in adults with extrahepatic portal venous obstruction: a prospective randomized study.
SA Zargar, G Javid, BA Khan, OJ Shah, GN Yattoo, AH Shah, GM Gulzar, J Singh, NA Shah, HM Shafi, Gastrointest Endosc. 2005 Jan:58-66

 

Endoscopic outcome beyond esophageal variceal eradication in children with extrahepatic portal venous obstruction.
S Itha, SK Yachha, J Pediatr Gastroenterol Nutr. 2006 Feb:196-200

 

Hemorheology in patients with liver cirrhosis: special emphasis on its relation to severity of esophageal variceal bleeding.
TT Liu, WJ Wong, MC Hou, HC Lin, FY Chang, SD Lee, J Gastroenterol Hepatol. 2006 May:908-13

 

The prevalence and risk factors associated with esophageal varices in subjects with hepatitis C and advanced fibrosis.
AJ Sanyal, RJ Fontana, AM Di Bisceglie, JE Everhart, MC Doherty, GT Everson, JA Donovan, PF Malet, S Mehta, MY Sheikh, AE Reid, MG Ghany, DR Gretch, Halt-C Trial Group, Gastrointest Endosc. 2006 Dec:855-64