Gastroesophageal reflux disease (GERD) can be defined as troublesome symptoms sufficient to impair an individual’s quality of life, or injury or complications that result from the retrograde flow of gastric contents into the esophagus, oropharynx, and/or respiratory tract. Reflux-induced symptoms, erosive esophagitis, and long-term complications may have severely deleterious effects on daily activities, work productivity, sleep, and quality of life. The Montreal definition of GERD states that “troublesome symptoms” may be considered to be moderate to severe symptoms that occur on one or more days per week.
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